TWO-DIMENSIONAL-MATERIAL-BASED FIELD-EFFECT TRANSISTOR FOR DETECTION OF PATHOGENS AND METHODS FOR MANUFACTURING
In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide (104) that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two- dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed..
| Medienart: |
|
|---|
Patent| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Europäisches Patentamt - (2022) vom: 19. Mai Zur Gesamtaufnahme - year:2022 |
|---|
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
MAHJOURI-SAMANI MASOUD [VerfasserIn] |
|---|
| Links: |
Volltext [kostenfrei] |
|---|
| Themen: |
Sonstige Themen: |
|---|
| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-05-19, Last update posted on www.tib.eu: 2023-09-28, Last updated: 2023-09-29 |
|---|
| Patentnummer: |
WO2022103731 |
|---|
| Förderinstitution / Projekttitel: |
|
|---|
| PPN (Katalog-ID): |
EPA002134535 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | EPA002134535 | ||
| 003 | DE-627 | ||
| 005 | 20240327214755.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240327s2022 xx |||||o 00| ||eng c | ||
| 035 | |a (DE-627)EPA002134535 | ||
| 035 | |a (EPA)WO2022103731 | ||
| 035 | |a (EPA)78819678 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 0 | |a MAHJOURI-SAMANI MASOUD |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a TWO-DIMENSIONAL-MATERIAL-BASED FIELD-EFFECT TRANSISTOR FOR DETECTION OF PATHOGENS AND METHODS FOR MANUFACTURING |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Source: www.epo.org (no modifications made), First posted: 2022-05-19, Last update posted on www.tib.eu: 2023-09-28, Last updated: 2023-09-29 | ||
| 520 | |a In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide (104) that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two- dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed. | ||
| 650 | 4 | |a B82Y: Specific uses or applications of nanostructures; measurement or analysis of nanostructures; manufacture or treatment of nanostructures | |
| 650 | 4 | |a G01N: Investigating or analysing materials by determining their chemical or physical properties (measuring or testing processes other than immunoassay, involving enzymes or microorganisms c12m, c12q) | |
| 650 | 4 | |a tec | |
| 650 | 4 | |a phy | |
| 650 | 4 | |a 615 | |
| 700 | 0 | |a HAMILTON MICHAEL C |4 aut | |
| 700 | 0 | |a KURODA MARCELO |4 aut | |
| 700 | 0 | |a HASIM SAHAR |4 aut | |
| 700 | 0 | |a FATHI-HAFSHEJANI PARVIN |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Europäisches Patentamt |g (2022) vom: 19. Mai |
| 773 | 1 | 8 | |g year:2022 |g day:19 |g month:05 |
| 856 | 4 | 0 | |u https://worldwide.espacenet.com/patent/search/family/78819678/publication/WO2022103731A1?q=WO2022103731 |z kostenfrei |3 Volltext |
| 912 | |a GBV_EPA | ||
| 951 | |a AR | ||
| 952 | |j 2022 |b 19 |c 05 | ||