NOVEL POLYMER
A functionalised polymer comprising a polymer partially functionalised with: a plurality of photocrosslinkable moieties linked to the polymer, each photocrosslinkable moiety comprising a reactive functionality capable of photocrosslinking; and a plurality of cell adhesion moieties each linked to the polymer via a linker, each cell adhesion moiety comprising a cell adhesion motif, and wherein the functionalised polymer further comprises a plurality of functional groups capable of ionic crosslinking with an ionic crosslinking agent. A method for forming a liquified polymer composition comprising cells from a tissue sample, the method comprising: providing a tissue sample comprising cells; contacting the sample with the functionalised polymer in binding conditions, said binding conditions being conditions that enable binding of cells in the sample to the functionalised polymer, so that said cells are bound to the functionalised polymer; culturing the cells bound to the polymer under conditions and for a time that allows the cell number to increase; providing conditions to induce a solid to liquid phase change of the functionalised polymer; thereby forming a liquified polymer composition comprising cells from a tissue sample..
| Medienart: |
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 08. Juni Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
CHOONG PETER [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-06-08, Last update posted on www.tib.eu: 2023-09-28, Last updated: 2023-09-29 |
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| Patentnummer: |
WO2023097372 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA001982478 |
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| 245 | 1 | 0 | |a NOVEL POLYMER |
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| 520 | |a A functionalised polymer comprising a polymer partially functionalised with: a plurality of photocrosslinkable moieties linked to the polymer, each photocrosslinkable moiety comprising a reactive functionality capable of photocrosslinking; and a plurality of cell adhesion moieties each linked to the polymer via a linker, each cell adhesion moiety comprising a cell adhesion motif, and wherein the functionalised polymer further comprises a plurality of functional groups capable of ionic crosslinking with an ionic crosslinking agent. A method for forming a liquified polymer composition comprising cells from a tissue sample, the method comprising: providing a tissue sample comprising cells; contacting the sample with the functionalised polymer in binding conditions, said binding conditions being conditions that enable binding of cells in the sample to the functionalised polymer, so that said cells are bound to the functionalised polymer; culturing the cells bound to the polymer under conditions and for a time that allows the cell number to increase; providing conditions to induce a solid to liquid phase change of the functionalised polymer; thereby forming a liquified polymer composition comprising cells from a tissue sample. | ||
| 650 | 4 | |a C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000) | |
| 650 | 4 | |a cet | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a med | |
| 650 | 4 | |a che | |
| 650 | 4 | |a A61L: Methods or apparatus for sterilising materials or objects in general; disinfection, sterilisation, or deodorisation of air; chemical aspects of bandages, dressings, absorbent pads, or surgical articles; materials for bandages, dressings, absorbent pads, or surgical articles (preservation of bodies or disinfecting characterised by the agent employed a01n;preserving, e.g. sterilising, food or foodstuffs a23;preparations for medical, dental or toilet purposes a61k) | |
| 650 | 4 | |a C08J: Working-up; general processes of compounding; after-treatment not covered by subclasses c08b, c08c, c08f, c08g or c08h (working, e.g. shaping, of plastics b29) | |
| 650 | 4 | |a C08B: Polysaccharides; derivatives thereof (polysaccharides containing less than six saccharide radicals attached to each other by glycosidic linkages c07h;fermentation or enzyme-using processes c12p0019000000;production of cellulose d21) | |
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