TWO-DIMENSIONAL-MATERIAL-BASED FIELD-EFFECT TRANSISTOR FOR DETECTION OF PATHOGENS AND METHODS FOR MANUFACTURING
In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide (104) that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two- dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed..
Medienart: |
Patent |
---|
Erscheinungsjahr: |
2022 |
---|---|
Erschienen: |
2022 |
Enthalten in: |
Europäisches Patentamt - (2022) vom: 19. Mai Zur Gesamtaufnahme - year:2022 |
---|
Sprache: |
Englisch |
---|
Beteiligte Personen: |
MAHJOURI-SAMANI MASOUD [VerfasserIn] |
---|
Links: |
Volltext [kostenfrei] |
---|
Themen: |
Sonstige Themen: |
---|
Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2022-05-19, Last update posted on www.tib.eu: 2023-09-25, Last updated: 2023-09-29 |
---|
Patentnummer: |
CA3201465 |
---|
Förderinstitution / Projekttitel: |
|
---|
PPN (Katalog-ID): |
EPA001721860 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | EPA001721860 | ||
003 | DE-627 | ||
005 | 20240327213247.0 | ||
007 | cr uuu---uuuuu | ||
008 | 240327s2022 xx |||||o 00| ||eng c | ||
035 | |a (DE-627)EPA001721860 | ||
035 | |a (EPA)CA3201465 | ||
035 | |a (EPA)78819678 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 0 | |a MAHJOURI-SAMANI MASOUD |e verfasserin |4 aut | |
245 | 1 | 0 | |a TWO-DIMENSIONAL-MATERIAL-BASED FIELD-EFFECT TRANSISTOR FOR DETECTION OF PATHOGENS AND METHODS FOR MANUFACTURING |
264 | 1 | |c 2022 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Source: www.epo.org (no modifications made), First posted: 2022-05-19, Last update posted on www.tib.eu: 2023-09-25, Last updated: 2023-09-29 | ||
520 | |a In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide (104) that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two- dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed. | ||
650 | 4 | |a B82Y: Specific uses or applications of nanostructures; measurement or analysis of nanostructures; manufacture or treatment of nanostructures | |
650 | 4 | |a G01N: Investigating or analysing materials by determining their chemical or physical properties (measuring or testing processes other than immunoassay, involving enzymes or microorganisms c12m, c12q) | |
650 | 4 | |a phy | |
650 | 4 | |a tec | |
650 | 4 | |a 615 | |
700 | 0 | |a HAMILTON MICHAEL C |4 aut | |
700 | 0 | |a KURODA MARCELO |4 aut | |
700 | 0 | |a HASIM SAHAR |4 aut | |
700 | 0 | |a FATHI-HAFSHEJANI PARVIN |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Europäisches Patentamt |g (2022) vom: 19. Mai |
773 | 1 | 8 | |g year:2022 |g day:19 |g month:05 |
856 | 4 | 0 | |u https://worldwide.espacenet.com/patent/search/family/78819678/publication/CA3201465A1?q=CA3201465 |z kostenfrei |3 Volltext |
912 | |a GBV_EPA | ||
951 | |a AR | ||
952 | |j 2022 |b 19 |c 05 |