Triazolo-pyrimidine analogs for treatment of diseases associated with wia syndrome RECQ helicase (WRN) inhibition

The present invention provides compounds having formula (I): wherein R1, R2, R3, R4, R5, R26, R27, y, R, M, W, L, V, T, Y, J, K and A are as described herein, or pharmaceutically acceptable salts thereof, therapeutic uses of the compounds, uses of the compounds as research type chemicals, pharmaceutical compositions and combinations comprising the compounds, and processes for making compounds of the invention. # imgabs0 #.

Medienart:

Patent

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Europäisches Patentamt - (2024) vom: 19. Jan. Zur Gesamtaufnahme - year:2024

Sprache:

Englisch

Beteiligte Personen:

BORDAS VINCENT [VerfasserIn]
BULLEN JULIE [VerfasserIn]
DECKER ANDREAS [VerfasserIn]
FUREGATTI MAURIZIO [VerfasserIn]
GOGNIAT GUILLAUME [VerfasserIn]
GONG WANBEN [VerfasserIn]
HARMON JOHN [VerfasserIn]
HINRICHS JUERGEN HANS-HERMANN [VerfasserIn]
HOLZER PHILIPP [VerfasserIn]
LIMAM FATMA [VerfasserIn]
MOEBITZ HENRIK [VerfasserIn]
NOCITO STEFANO [VerfasserIn]
PLATTNER STEFAN [VerfasserIn]
SCHMIEDEBERG NIKO [VerfasserIn]
SCHOEPFER JOSEPH [VerfasserIn]
SOTO JULIO [VerfasserIn]
STRONG ROLAND [VerfasserIn]
YAO SHUPING [VerfasserIn]
YU HUANGCHAO [VerfasserIn]
ZECRI FREDERIC [VerfasserIn]
ZHANG SISI [VerfasserIn]

Links:

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Themen:

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Anmerkungen:

Source: www.epo.org (no modifications made), First posted: 2024-01-19, Last update posted on www.tib.eu: 2024-04-22, Last updated: 2024-04-26

Patentnummer:

CN117425657

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

EPA001564587