METHOD FOR CULTURING CELL AND KIT AND DEVICE THEREFOR
To provide a method for incubation or culture for inducing growth, activation, co-stimulation and/or stimulation of survival, of a composition of cells such as a mass of lymphocytes.SOLUTION: There is provided a method for culturing T cells, including following steps of: (a) incubating a composition including T cells, under existence of a receptor binding substance, the receptor binding substance is (i) reversibly coupled to a reagent including a plurality of binding sites which can be reversibly bound to the receptor binding substance, and (ii) specifically binds to a molecule on the surfaces of the T cells, in a manner of inducing or modulating a signal on the T cell in the composition; and (b) breaking reverse binding between the receptor binding substance and the reagent, within 5 days since start of the incubation, for generating the cultured T cell.SELECTED DRAWING: None.
| Medienart: |
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 02. Okt. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
LOTHAR GERMEROTH [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-10-02, Last update posted on www.tib.eu: 2024-04-03, Last updated: 2024-04-09 |
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| Patentnummer: |
JP2023138707 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA001116223 |
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| 520 | |a To provide a method for incubation or culture for inducing growth, activation, co-stimulation and/or stimulation of survival, of a composition of cells such as a mass of lymphocytes.SOLUTION: There is provided a method for culturing T cells, including following steps of: (a) incubating a composition including T cells, under existence of a receptor binding substance, the receptor binding substance is (i) reversibly coupled to a reagent including a plurality of binding sites which can be reversibly bound to the receptor binding substance, and (ii) specifically binds to a molecule on the surfaces of the T cells, in a manner of inducing or modulating a signal on the T cell in the composition; and (b) breaking reverse binding between the receptor binding substance and the reagent, within 5 days since start of the incubation, for generating the cultured T cell.SELECTED DRAWING: None | ||
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000) | |
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