PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF
The present invention relates to prodrugs of (S)- or (R)-ketamine, including isotopically labeled ketamine, compositions and uses thereof. Compounds having formula (IVa) or (IVb) as the prodrugs of (S)- or (R)-ketamine, including isotopically labeled ketamine, and pharmaceutical compositions comprising the compounds provided herein are used for treating or preventing a CNS disease. More particularly, the related diseases to be treated or prevented include depression and pain. (see formula IVa)(see formula IVb).
| Medienart: |
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 14. März Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
XIANG JIA-NING [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-03-14, Last update posted on www.tib.eu: 2024-04-01, Last updated: 2024-04-09 |
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| Patentnummer: |
CA3087912 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA001087460 |
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| 520 | |a The present invention relates to prodrugs of (S)- or (R)-ketamine, including isotopically labeled ketamine, compositions and uses thereof. Compounds having formula (IVa) or (IVb) as the prodrugs of (S)- or (R)-ketamine, including isotopically labeled ketamine, and pharmaceutical compositions comprising the compounds provided herein are used for treating or preventing a CNS disease. More particularly, the related diseases to be treated or prevented include depression and pain. (see formula IVa)(see formula IVb) | ||
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