TISSUE-DERIVED MATRIKINE COMPOSITIONS AND METHODS THEREFOR
A composition for topical administration to an epithelium is disclosed. The composition comprises a deconstructed matrisome including one or more enzymatically fragmented peptides derived from biological tissue. The composition further comprises one or more pharmaceutically acceptable or cosmetically acceptable excipients. The deconstructed matrisome may be fragmented through degradation by one or more enzymes to produce the one or more peptides. The one or more peptides may be configured to retain cell signaling ability, thereby promoting one or more of tissue homeostasis, tissue repair, and tissue regeneration. The composition may be used to treat a tissue such as skin tissue exhibiting scarring, acne, eczema, psoriasis, and other skin conditions..
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Patent| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Europäisches Patentamt - (2024) vom: 25. Jan. Zur Gesamtaufnahme - year:2024 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
O'NEILL JOHN D [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2024-01-25, Last update posted on www.tib.eu: 2024-03-06, Last updated: 2024-03-15 |
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| Patentnummer: |
US2024024431 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA000688088 |
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| 520 | |a A composition for topical administration to an epithelium is disclosed. The composition comprises a deconstructed matrisome including one or more enzymatically fragmented peptides derived from biological tissue. The composition further comprises one or more pharmaceutically acceptable or cosmetically acceptable excipients. The deconstructed matrisome may be fragmented through degradation by one or more enzymes to produce the one or more peptides. The one or more peptides may be configured to retain cell signaling ability, thereby promoting one or more of tissue homeostasis, tissue repair, and tissue regeneration. The composition may be used to treat a tissue such as skin tissue exhibiting scarring, acne, eczema, psoriasis, and other skin conditions. | ||
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
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| 650 | 4 | |a A61Q: Specific use of cosmetics or similar toilet preparations | |
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