VACCINE IMMUNOGENS

An immunogenic composition comprising: a) one or more plasmodium-derived ribosomal or ribosomal associated protein or immunogenic fragment thereof which has a sequence which is at least about 80%, 85%, 90%, 95%, 98%, 99% or 100% identical to a ribosomal or ribosomal associated protein or an immunogenic fragment of a ribosomal or ribosomal associated protein recited in Figure 1; or a ribosomal or ribosomal associated protein or peptide or immunogenic fragment thereof as recited in Figure 2 or Figure 3; and/or b) a polynucleotide encoding one or more protein, peptide or immunogenic fragment of a); wherein the immunogenic composition is for use in eliciting an immune response in a subject to treat or prevent malaria. Also provided areplasmodium-derived ETRAMPs and/or histones, or immunogenic fragments thereof, for use in eliciting an immune response in a subject, preferably to treat or prevent malaria..

Medienart:

Patent

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Europäisches Patentamt - (2024) vom: 28. Feb. Zur Gesamtaufnahme - year:2024

Sprache:

Englisch

Beteiligte Personen:

HILL ADRIAN VIVIAN SINTON [VerfasserIn]
BETTENCOURT PAULO JORGE GONCALVES DE [VerfasserIn]
SPENCER ALEXANDRA JANE [VerfasserIn]
TERNETTE NICOLA MARIA NATHALIE [VerfasserIn]
SALMAN AHMED MAHMOUD AHMED AHMED [VerfasserIn]
JUNQUEIRA CAROLINE FURTADO [VerfasserIn]
GAZZINELLI RICARDO TOSTES [VerfasserIn]
BARBOSA CAMILA RAQUEL RODRIGUES [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

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Anmerkungen:

Source: www.epo.org (no modifications made), First posted: 2024-02-28, Last update posted on www.tib.eu: 2024-03-14, Last updated: 2024-03-22

Patentnummer:

EP4275700

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

EPA000650234