Neutralization blocking agent for blocking virus from infecting cells as well as preparation method and application of neutralization blocking agent
The invention provides a neutralization blocking agent for blocking virus infected cells and a preparation method and application of the neutralization blocking agent, and the neutralization blocking agent comprises a first functional area G and a second functional area S which have specific binding viruses, and a third functional area Ng with a neutralizing group. The third functional area Ng carries charges which are the same as the cell surface and/or virus receptor protein and are opposite to the fusion functional protein of the virus in electrical property, and due to the fact that the charges which are opposite to the fusion functional protein of the virus in electrical property are carried, the binding capacity of the blocking agent and the virus can be improved; and the neutralized virus carries the same charges as the cell surface and/or the virus receptor protein, so that the electrostatic binding of the virus and the cell and/or the virus receptor protein is blocked, and the blocking capability of the virus on the infection of the cell is improved..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 29. Dez. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
GUO MIN [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-12-29, Last update posted on www.tib.eu: 2024-03-13, Last updated: 2024-03-22 |
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| Patentnummer: |
CN117304333 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA000598291 |
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| 245 | 1 | 0 | |a Neutralization blocking agent for blocking virus from infecting cells as well as preparation method and application of neutralization blocking agent |
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| 520 | |a The invention provides a neutralization blocking agent for blocking virus infected cells and a preparation method and application of the neutralization blocking agent, and the neutralization blocking agent comprises a first functional area G and a second functional area S which have specific binding viruses, and a third functional area Ng with a neutralizing group. The third functional area Ng carries charges which are the same as the cell surface and/or virus receptor protein and are opposite to the fusion functional protein of the virus in electrical property, and due to the fact that the charges which are opposite to the fusion functional protein of the virus in electrical property are carried, the binding capacity of the blocking agent and the virus can be improved; and the neutralized virus carries the same charges as the cell surface and/or the virus receptor protein, so that the electrostatic binding of the virus and the cell and/or the virus receptor protein is blocked, and the blocking capability of the virus on the infection of the cell is improved. | ||
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| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
| 650 | 4 | |a C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000) | |
| 650 | 4 | |a C07K: Peptides (peptides containing β-lactam rings c07d;cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, c07d;ergot alkaloids of the cyclic peptide type c07d0519020000; single cell proteins, enzymes c12n;genetic engineering processes for obtaining peptides c12n0015000000) | |
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