ULTRASOUND ARRAYS FOR ENHANCED SONODYNAMIC THERAPY FOR TREATING CANCER

Ultrasound transducer element arrays using acoustic ensonification drive patterns via a patient interface for sonosensitizer activation in sonodynamic therapy. Incoherent acoustic field generation varying phase, frequencies, and/or amplitude via controlled delivery of low intensity planar acoustic waves. Method includes generating a first and a second signal to generate respective acoustic ensonification drive patterns with phase, frequency, and amplitude and generating at least one relative phase, frequency or amplitude difference to generate a third incoherent acoustic ensonification pattern to activate a sonosensitizer. Calibration and complementary therapy procedures to improve cell susceptibility of cells to sonodynamic therapy are disclosed..

Medienart:

Patent

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Europäisches Patentamt - (2023) vom: 26. Okt. Zur Gesamtaufnahme - year:2023

Sprache:

Englisch

Beteiligte Personen:

AGARWAL VIJAY [VerfasserIn]
ELIASON BRADEN [VerfasserIn]
LING JEREMY [VerfasserIn]
BALLARD JOHN [VerfasserIn]
MILLER GREGG [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

Sonstige Themen:
615
A61K: Preparations for medical, dental, or toilet purpose (...)
A61N: Electrotherapy; magnetotherapy; radiation therapy; (...)
B06B: Generating or transmitting mechanical vibrations in (...)
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med

Anmerkungen:

Source: www.epo.org (no modifications made), First posted: 2023-10-26, Last update posted on www.tib.eu: 2024-04-17, Last updated: 2024-04-26

Patentnummer:

US2023338754

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

EPA000507423