Benzapac sodium ester tablet and preparation method thereof
The invention provides a preparation method of a bentonate tablet. According to the method, the benzene sodium ester raw material and part of the hydrophilic diluent are mixed and micronized, the micronized composition powder after micronization is free of agglomeration, good fluidity is kept, and subsequent processing is facilitated, so that time is saved, time consumed by the whole process of tablet preparation is shortened, and the method is particularly suitable for industrial large-scale production. The bentonate tablet prepared from the micronized composition has better dissolution rate, and the dissolution performance of the bentonate tablet is basically consistent with that of an original tablet; the formula and the process are combined, and the prepared bentonate tablet has the advantage that the content change of total impurities and single impurities is small at the same time..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 19. Dez. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
ZHAO YUWEI [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-12-19, Last update posted on www.tib.eu: 2024-03-13, Last updated: 2024-03-22 |
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| Patentnummer: |
CN117243914 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA000457868 |
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| 245 | 1 | 0 | |a Benzapac sodium ester tablet and preparation method thereof |
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| 500 | |a Source: www.epo.org (no modifications made), First posted: 2023-12-19, Last update posted on www.tib.eu: 2024-03-13, Last updated: 2024-03-22 | ||
| 520 | |a The invention provides a preparation method of a bentonate tablet. According to the method, the benzene sodium ester raw material and part of the hydrophilic diluent are mixed and micronized, the micronized composition powder after micronization is free of agglomeration, good fluidity is kept, and subsequent processing is facilitated, so that time is saved, time consumed by the whole process of tablet preparation is shortened, and the method is particularly suitable for industrial large-scale production. The bentonate tablet prepared from the micronized composition has better dissolution rate, and the dissolution performance of the bentonate tablet is basically consistent with that of an original tablet; the formula and the process are combined, and the prepared bentonate tablet has the advantage that the content change of total impurities and single impurities is small at the same time. | ||
| 650 | 4 | |a A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d) | |
| 650 | 4 | |a A61P: Specific therapeutic activity of chemical compounds or medicinal preparations | |
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| 773 | 1 | 8 | |g year:2023 |g day:19 |g month:12 |
| 856 | 4 | 0 | |u https://worldwide.espacenet.com/patent/search/family/89131829/publication/CN117243914A1?q=CN117243914 |z kostenfrei |3 Volltext |
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