Fish miRNA and application thereof
The invention discloses a fish miRNA and application thereof, the fish is paralichthys olivaceus, the name of the miRNA is pol-miR-n199-3p, and the base sequence of the miRNA is as shown in SEQ ID NO. 1. According to the present invention, the pol-miR-n199-3p is adopted as the fish immunomodulatory molecule, the synthesized pol-miR-n199-3p simulant is prepared into the antibacterial preparation, and after the antibacterial preparation is injected into the fish body, the vibrio anguillarum infection paralichthys olivaceus can be significantly inhibited (P < 0.05), the antibacterial immunocompetence of the paralichthys olivaceus can be improved, and the new way is provided for efficiently enhancing the antibacterial immunocompetence of the economically cultured fish..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 12. Sept. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
NING XIANHUI [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-09-12, Last update posted on www.tib.eu: 2024-03-12, Last updated: 2024-03-15 |
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| Patentnummer: |
CN116732029 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA000388319 |
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| 520 | |a The invention discloses a fish miRNA and application thereof, the fish is paralichthys olivaceus, the name of the miRNA is pol-miR-n199-3p, and the base sequence of the miRNA is as shown in SEQ ID NO. 1. According to the present invention, the pol-miR-n199-3p is adopted as the fish immunomodulatory molecule, the synthesized pol-miR-n199-3p simulant is prepared into the antibacterial preparation, and after the antibacterial preparation is injected into the fish body, the vibrio anguillarum infection paralichthys olivaceus can be significantly inhibited (P < 0.05), the antibacterial immunocompetence of the paralichthys olivaceus can be improved, and the new way is provided for efficiently enhancing the antibacterial immunocompetence of the economically cultured fish. | ||
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| 650 | 4 | |a C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000) | |
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