METHOD FOR UTILIZING IN-SILICO HEART DISEASE DATABASE, PROGRAM FOR UTILIZING IN-SILICO HEART DISEASE DATABASE, AND INFORMATION PROCESSING DEVICE
The present invention constructs an information processing technology which utilizes an "in-silico heart disease database", and makes it possible to improve the prediction accuracy of developing heart diseases, suitably treat same, and furthermore efficiently develop a medicine. The present invention inputs, to a classifier which automatically diagnoses heart diseases, an electrocardiography or the like acquired from a database, which preserves simulation results of virtual disease heart models in which various factors pertaining to heart diseases are varied, namely, an "in-silico heart disease database", compares distributions of factor variation amounts in a positive group and a negative group, and specifies, as biomarkers, effect factors pertaining to the heart diseases from the comparison result. In addition, by identifying, on the in-silico heart disease database, a heart disease model having an electrocardiogram similar to a real electrocardiogram of an individual, precise diagnosis of the individual is conveniently performed. Furthermore, a medicine development process is made efficient by extracting a group having a certain feature from the in-silico heart disease database and conveniently evaluating the medication effect of same..
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Patent| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Europäisches Patentamt - (2024) vom: 22. Feb. Zur Gesamtaufnahme - year:2024 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
HISADA TOSHIAKI [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2024-02-22, Last update posted on www.tib.eu: 2024-03-27, Last updated: 2024-03-29 |
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| Patentnummer: |
WO2024038618 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA000350532 |
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| 520 | |a The present invention constructs an information processing technology which utilizes an "in-silico heart disease database", and makes it possible to improve the prediction accuracy of developing heart diseases, suitably treat same, and furthermore efficiently develop a medicine. The present invention inputs, to a classifier which automatically diagnoses heart diseases, an electrocardiography or the like acquired from a database, which preserves simulation results of virtual disease heart models in which various factors pertaining to heart diseases are varied, namely, an "in-silico heart disease database", compares distributions of factor variation amounts in a positive group and a negative group, and specifies, as biomarkers, effect factors pertaining to the heart diseases from the comparison result. In addition, by identifying, on the in-silico heart disease database, a heart disease model having an electrocardiogram similar to a real electrocardiogram of an individual, precise diagnosis of the individual is conveniently performed. Furthermore, a medicine development process is made efficient by extracting a group having a certain feature from the in-silico heart disease database and conveniently evaluating the medication effect of same. | ||
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