Pelteobagrus fulvidraco miRNA and application thereof
The invention discloses a pelteobagrus fulvidraco miRNA (micro ribonucleic acid) and application thereof. The pelteobagrus fulvidraco miRNA is pfu-miR-n001-3p, and the nucleotide sequence of the pelteobagrus fulvidraco miRNA is as shown in SEQ ID NO. 1. The pelteobagrus fulvidraco miRNA disclosed by the invention is the pfu-miR-n001-3p found for the first time, and can be combined with the pelteobagrus fulvidraco ACOX1 gene in a targeted manner. According to the miRNA simulant of the pelteobagrus fulvidraco, disclosed by the invention, the expression quantity of pfu-miR-n001-3p is increased, and the expression of an ACOX1 gene is remarkably inhibited, so that lipid accumulation is promoted, and finally, the anti-aeromonas veronii infection immune response of the pelteobagrus fulvidraco is regulated..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 03. Okt. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
NING XIANHUI [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-10-03, Last update posted on www.tib.eu: 2024-03-12, Last updated: 2024-03-15 |
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| Patentnummer: |
CN116836983 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA000254533 |
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| 520 | |a The invention discloses a pelteobagrus fulvidraco miRNA (micro ribonucleic acid) and application thereof. The pelteobagrus fulvidraco miRNA is pfu-miR-n001-3p, and the nucleotide sequence of the pelteobagrus fulvidraco miRNA is as shown in SEQ ID NO. 1. The pelteobagrus fulvidraco miRNA disclosed by the invention is the pfu-miR-n001-3p found for the first time, and can be combined with the pelteobagrus fulvidraco ACOX1 gene in a targeted manner. According to the miRNA simulant of the pelteobagrus fulvidraco, disclosed by the invention, the expression quantity of pfu-miR-n001-3p is increased, and the expression of an ACOX1 gene is remarkably inhibited, so that lipid accumulation is promoted, and finally, the anti-aeromonas veronii infection immune response of the pelteobagrus fulvidraco is regulated. | ||
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