PREPARATION METHOD FOR TUMOR INFILTRATING LYMPHOCYTE AND USE THEREOF
Provided are a preparation method for a tumor-infiltrating lymphocyte, and use thereof, particularly relating to a method for culturing a tumor-infiltrating lymphocyte, comprising: subjecting a TIL, which is derived from tumor tissues and not expanded in vitro, to in vitro expansion of at least one stage, and wherein the TIL is contacted with a CD28 agonist in the in vitro expansion of at least one stage. Further provided is a method for preventing and/or treating tumors by using the tumor-infiltrating lymphocyte..
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Patent| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Europäisches Patentamt - (2024) vom: 08. Feb. Zur Gesamtaufnahme - year:2024 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
LIU YARONG [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2024-02-08, Last update posted on www.tib.eu: 2024-04-17, Last updated: 2024-04-26 |
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| Patentnummer: |
US2024043801 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA000149179 |
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| 520 | |a Provided are a preparation method for a tumor-infiltrating lymphocyte, and use thereof, particularly relating to a method for culturing a tumor-infiltrating lymphocyte, comprising: subjecting a TIL, which is derived from tumor tissues and not expanded in vitro, to in vitro expansion of at least one stage, and wherein the TIL is contacted with a CD28 agonist in the in vitro expansion of at least one stage. Further provided is a method for preventing and/or treating tumors by using the tumor-infiltrating lymphocyte. | ||
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