Microsensor for detecting hemoglobin based on nanogold doped patterned graphene electrode and preparation method thereof
The invention discloses a nanogold-doped patterned graphene electrode-based microsensor for detecting hemoglobin and a preparation method of the nanogold-doped patterned graphene electrode-based microsensor. A reasonable material design is combined with a low-temperature plasma surface treatment technology and a chiral molecular layer assembly technology; constructing a chiral molecular layer activated nanogold doping-based patterned graphene electrode, and packaging the electrode into a microsensor for detecting hemoglobin; due to the synergistic effect of the graphene sheet layer and the nanogold, the spiral electromagnetic field of the chiral molecular layer and the regulation and modification effect of plasma on the electrode substrate, the sensor has high sensitivity and low detection limit on hemoglobin sensing detection signals, and the sensing detection lower limit reaches 10-100 mg/mL; the electrochemical sensing detection of hemoglobin can be realized in a neutral environment, the biomolecular conformation of hemoglobin can be maintained, and the accuracy and sensitivity of sensing and detection are further improved; the preparation method of the electrode and the microsensor is simple and efficient, does not need dye sensitization, and is low in cost..
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Patent| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Europäisches Patentamt - (2023) vom: 22. Dez. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Beteiligte Personen: |
ZHANG WENYAN [VerfasserIn] |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
Sonstige Themen: |
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| Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2023-12-22, Last update posted on www.tib.eu: 2024-03-13, Last updated: 2024-03-22 |
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| Patentnummer: |
CN117269274 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
EPA000111643 |
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| 245 | 1 | 0 | |a Microsensor for detecting hemoglobin based on nanogold doped patterned graphene electrode and preparation method thereof |
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| 520 | |a The invention discloses a nanogold-doped patterned graphene electrode-based microsensor for detecting hemoglobin and a preparation method of the nanogold-doped patterned graphene electrode-based microsensor. A reasonable material design is combined with a low-temperature plasma surface treatment technology and a chiral molecular layer assembly technology; constructing a chiral molecular layer activated nanogold doping-based patterned graphene electrode, and packaging the electrode into a microsensor for detecting hemoglobin; due to the synergistic effect of the graphene sheet layer and the nanogold, the spiral electromagnetic field of the chiral molecular layer and the regulation and modification effect of plasma on the electrode substrate, the sensor has high sensitivity and low detection limit on hemoglobin sensing detection signals, and the sensing detection lower limit reaches 10-100 mg/mL; the electrochemical sensing detection of hemoglobin can be realized in a neutral environment, the biomolecular conformation of hemoglobin can be maintained, and the accuracy and sensitivity of sensing and detection are further improved; the preparation method of the electrode and the microsensor is simple and efficient, does not need dye sensitization, and is low in cost. | ||
| 650 | 4 | |a tec | |
| 650 | 4 | |a G01N: Investigating or analysing materials by determining their chemical or physical properties (measuring or testing processes other than immunoassay, involving enzymes or microorganisms c12m, c12q) | |
| 650 | 4 | |a phy | |
| 650 | 4 | |a B82Y: Specific uses or applications of nanostructures; measurement or analysis of nanostructures; manufacture or treatment of nanostructures | |
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| 700 | 0 | |a GUAN HANGMIN |4 aut | |
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| 700 | 0 | |a YE YUANFENG |4 aut | |
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