Bovine Pluripotent Stem Cells: Current Status and Prospects
Pluripotent stem cells (PSCs) can differentiate into three germ layers and diverse autologous cell lines. Since cattle are the most commonly used large domesticated animals, an important food source, and bioreactors, great efforts have been made to establish bovine PSCs (bPSCs). bPSCs have great potential in bovine breeding and reproduction, modeling in vitro differentiation, imitating cancer development, and modeling diseases. Currently, bPSCs mainly include bovine embryonic stem cells (bESCs), bovine induced pluripotent stem cells (biPSCs), and bovine expanded potential stem cells (bEPSCs). Establishing stable bPSCs in vitro is a critical scientific challenge, and researchers have made numerous efforts to this end. In this review, the category of PSC pluripotency; the establishment of bESCs, biPSCs, and bEPSCs and its challenges; and the application outlook of bPSCs are discussed, aiming to provide references for future research..
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2024 |
---|---|
Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
---|---|
Enthalten in: |
International Journal of Molecular Sciences - 25(2024), 4, p 2120 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Lanxin Chen [VerfasserIn] |
---|
Links: |
doi.org [kostenfrei] |
---|
Themen: |
Biology (General) |
---|
doi: |
10.3390/ijms25042120 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
DOAJ099634392 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | DOAJ099634392 | ||
003 | DE-627 | ||
005 | 20240414043810.0 | ||
007 | cr uuu---uuuuu | ||
008 | 240414s2024 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.3390/ijms25042120 |2 doi | |
035 | |a (DE-627)DOAJ099634392 | ||
035 | |a (DE-599)DOAJ7b99ec293e5e4820a3077d9df374b172 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
050 | 0 | |a QH301-705.5 | |
050 | 0 | |a QD1-999 | |
100 | 0 | |a Lanxin Chen |e verfasserin |4 aut | |
245 | 1 | 0 | |a Bovine Pluripotent Stem Cells: Current Status and Prospects |
264 | 1 | |c 2024 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
520 | |a Pluripotent stem cells (PSCs) can differentiate into three germ layers and diverse autologous cell lines. Since cattle are the most commonly used large domesticated animals, an important food source, and bioreactors, great efforts have been made to establish bovine PSCs (bPSCs). bPSCs have great potential in bovine breeding and reproduction, modeling in vitro differentiation, imitating cancer development, and modeling diseases. Currently, bPSCs mainly include bovine embryonic stem cells (bESCs), bovine induced pluripotent stem cells (biPSCs), and bovine expanded potential stem cells (bEPSCs). Establishing stable bPSCs in vitro is a critical scientific challenge, and researchers have made numerous efforts to this end. In this review, the category of PSC pluripotency; the establishment of bESCs, biPSCs, and bEPSCs and its challenges; and the application outlook of bPSCs are discussed, aiming to provide references for future research. | ||
650 | 4 | |a cattle | |
650 | 4 | |a embryonic stem cells | |
650 | 4 | |a potential stem cells | |
650 | 4 | |a induced pluripotent stem cells | |
650 | 4 | |a reprogramming | |
653 | 0 | |a Biology (General) | |
653 | 0 | |a Chemistry | |
700 | 0 | |a Bo Tang |e verfasserin |4 aut | |
700 | 0 | |a Guanghong Xie |e verfasserin |4 aut | |
700 | 0 | |a Rui Yang |e verfasserin |4 aut | |
700 | 0 | |a Boyang Zhang |e verfasserin |4 aut | |
700 | 0 | |a Yueqi Wang |e verfasserin |4 aut | |
700 | 0 | |a Yan Zhang |e verfasserin |4 aut | |
700 | 0 | |a Daozhen Jiang |e verfasserin |4 aut | |
700 | 0 | |a Xueming Zhang |e verfasserin |4 aut | |
773 | 0 | 8 | |i In |t International Journal of Molecular Sciences |d MDPI AG, 2003 |g 25(2024), 4, p 2120 |w (DE-627)DOAJ00014584X |x 14220067 |7 nnns |
773 | 1 | 8 | |g volume:25 |g year:2024 |g number:4, p 2120 |
856 | 4 | 0 | |u https://doi.org/10.3390/ijms25042120 |z kostenfrei |
856 | 4 | 0 | |u https://doaj.org/article/7b99ec293e5e4820a3077d9df374b172 |z kostenfrei |
856 | 4 | 0 | |u https://www.mdpi.com/1422-0067/25/4/2120 |z kostenfrei |
856 | 4 | 2 | |u https://doaj.org/toc/1661-6596 |y Journal toc |z kostenfrei |
856 | 4 | 2 | |u https://doaj.org/toc/1422-0067 |y Journal toc |z kostenfrei |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_DOAJ | ||
951 | |a AR | ||
952 | |d 25 |j 2024 |e 4, p 2120 |