Italian healthcare resource consumption for patients on hemodialysis treated for chronic kidney disease-associated pruritus (CKD-aP)

Background: Chronic kidney disease-associated pruritus (CKD-aP) affects patients on hemodialysis. This study identified hemodialysis patients presumably affected or not affected by CKD-aP and integrated healthcare costs, from the perspective of the Italian administrative healthcare data. Methods: Through cross-linkage of Italian administrative healthcare data collected between 2015 and 2017 (accrual period) in the database of Fondazione ReS (Ricerca e Salute), patients undergoing in-hospital/outpatient hemodialysis were selected. Cohorts with and without CKD-aP were created based on the presence/absence of CKD-aP-related treatment (according to common clinical practice and guidelines) supplies and assessed in terms of CKD-aP-related treatments and mean healthcare costs per capita paid by the Italian National Health Service (INHS). Results: Of 1,239 people on hemodialysis for ≥2 years, CKD-aP affected 218 patients. Patients with CKD-aP were older and with more comorbidities. During the follow-up year, on average, the INHS spent €37,065 per case, €31,286 per control and € 35,988 per non-CKD-aP subject. High-efficiency dialytic therapies performed to people on hemodialysis with CKD-aP largely weighed on the overall mean annual cost. Conclusions: This real-world study identified patients on chronic hemodialysis potentially treated for CKD-aP. Interestingly, high-efficiency dialysis seems the most frequent and expensive choice for the treatment of CKD-aP. The discovery of appropriate and effective treatments for this condition might offer cost offsets..

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:11

Enthalten in:

Global & Regional Health Technology Assessment - 11(2024), 1

Sprache:

Englisch ; Spanisch ; Italienisch

Beteiligte Personen:

Silvia Calabria [VerfasserIn]
Manenti Lucio [VerfasserIn]
Giulia Ronconi [VerfasserIn]
Carlo Piccinni [VerfasserIn]
Leonardo Dondi [VerfasserIn]
Letizia Dondi [VerfasserIn]
Antonella Pedrini [VerfasserIn]
Immacolata Esposito [VerfasserIn]
Alice Addesi [VerfasserIn]
Filippo Aucella [VerfasserIn]
Nello Martini [VerfasserIn]

Links:

doi.org [kostenfrei]
doaj.org [kostenfrei]
journals.aboutscience.eu [kostenfrei]
Journal toc [kostenfrei]
Journal toc [kostenfrei]

Themen:

Costs
Dialysis
End-stage kidney disease
Italy
Medical technology
RWE
Retrospective analysis

doi:

10.33393/grhta.2024.2696

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

DOAJ097595284