Prevalence of <i<Toxoplasma gondii</i< IgG Antibodies and Associated Risk Factors in Psychiatric Patients from Western Romania: A Cross-Sectional Study
Infection with the coccidian parasite <i<Toxoplasma gondii</i< was associated with an increased risk of several mental disorders. We conducted a case–control study of 464 consecutive psychiatric patients and assessed the prevalence of IgG antibodies against <i<T. gondii</i< and the potential risk factors associated with infection. <i<T. gondii</i<-specific antibodies were determined using a chemiluminescence assay. A questionnaire was utilized to assess the potential correlation between risk factors and <i<Toxoplasma gondii</i< seropositivity. IgG antibodies were found in 325 (70.04%) of the patients. We observed a higher likelihood of positive IgG antibodies against <i<Toxoplasma gondii</i< in older individuals, patients residing in rural areas, and females. We also noted associations between <i<Toxoplasma gondii</i< infection and certain risk factors, like activities that involve contact with soil, low-income levels, and limited educational attainment. Our findings indicate a high prevalence of <i<T. gondii</i< infection among psychiatric patients from Western Romania and provide new information regarding the potential risk factors associated with <i<T. gondii</i< in this population group. This study may serve as a foundation for future research and the development of preventive strategies..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
Microorganisms - 12(2024), 1, p 172 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sebastian Grada [VerfasserIn] |
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| Links: |
doi.org [kostenfrei] |
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| Themen: |
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| doi: |
10.3390/microorganisms12010172 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
DOAJ096174935 |
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| 520 | |a Infection with the coccidian parasite <i<Toxoplasma gondii</i< was associated with an increased risk of several mental disorders. We conducted a case–control study of 464 consecutive psychiatric patients and assessed the prevalence of IgG antibodies against <i<T. gondii</i< and the potential risk factors associated with infection. <i<T. gondii</i<-specific antibodies were determined using a chemiluminescence assay. A questionnaire was utilized to assess the potential correlation between risk factors and <i<Toxoplasma gondii</i< seropositivity. IgG antibodies were found in 325 (70.04%) of the patients. We observed a higher likelihood of positive IgG antibodies against <i<Toxoplasma gondii</i< in older individuals, patients residing in rural areas, and females. We also noted associations between <i<Toxoplasma gondii</i< infection and certain risk factors, like activities that involve contact with soil, low-income levels, and limited educational attainment. Our findings indicate a high prevalence of <i<T. gondii</i< infection among psychiatric patients from Western Romania and provide new information regarding the potential risk factors associated with <i<T. gondii</i< in this population group. This study may serve as a foundation for future research and the development of preventive strategies. | ||
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