Autoimmune Pancreatitis Type 1 with Biliary, Nasal, Testicular, and Pulmonary Involvement: A Case Report and a Systematic Review
Introduction: Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated condition associated with fibroinflammatory lesions that can occur at almost any anatomical site. It often presents as a multiorgan disease that may mimic malignancy, infection, or other immune-mediated conditions. Autoimmune pancreatitis (AIP) type 1 is the most prominent manifestation of IgG4-RD in the digestive tract, with common extra-pancreatic inflammation. We present the first patient with AIP and involvement of the testicles and nasal cavity. Patient and methods: A case of a patient with AIP type 1 and other organ involvement (bile ducts, testicles, nasal polyps, and lungs) is described. Additionally, a systematic review of AIP type 1 with testicular and nasal involvement was conducted. Results: The systematic review found two cases of AIP type 1 with testicular involvement and 143 cases with AIP type 1 with nasal cavity involvement. None of them had both testicular and nasal involvement. Conclusions: This is the first case of AIP type 1 with other organ involvement, including testicular and nasal involvement, to be described. The number of patients with nasal and testicular involvement described in the literature is low. Creating awareness of this rare clinical condition is necessary, especially due to the very effective available treatment with corticosteroids and rituximab..
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2023 |
---|---|
Erschienen: |
2023 |
Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
---|---|
Enthalten in: |
Journal of Clinical Medicine - 12(2023), 6340, p 6340 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Mourad Kourie [VerfasserIn] |
---|
Links: |
doi.org [kostenfrei] |
---|
Themen: |
Autoimmune |
---|
doi: |
10.3390/jcm12196340 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
DOAJ093221312 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | DOAJ093221312 | ||
003 | DE-627 | ||
005 | 20240413100827.0 | ||
007 | cr uuu---uuuuu | ||
008 | 240413s2023 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.3390/jcm12196340 |2 doi | |
035 | |a (DE-627)DOAJ093221312 | ||
035 | |a (DE-599)DOAJbbebdeedc8374c8b9b043feacca9feed | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 0 | |a Mourad Kourie |e verfasserin |4 aut | |
245 | 1 | 0 | |a Autoimmune Pancreatitis Type 1 with Biliary, Nasal, Testicular, and Pulmonary Involvement: A Case Report and a Systematic Review |
264 | 1 | |c 2023 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
520 | |a Introduction: Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated condition associated with fibroinflammatory lesions that can occur at almost any anatomical site. It often presents as a multiorgan disease that may mimic malignancy, infection, or other immune-mediated conditions. Autoimmune pancreatitis (AIP) type 1 is the most prominent manifestation of IgG4-RD in the digestive tract, with common extra-pancreatic inflammation. We present the first patient with AIP and involvement of the testicles and nasal cavity. Patient and methods: A case of a patient with AIP type 1 and other organ involvement (bile ducts, testicles, nasal polyps, and lungs) is described. Additionally, a systematic review of AIP type 1 with testicular and nasal involvement was conducted. Results: The systematic review found two cases of AIP type 1 with testicular involvement and 143 cases with AIP type 1 with nasal cavity involvement. None of them had both testicular and nasal involvement. Conclusions: This is the first case of AIP type 1 with other organ involvement, including testicular and nasal involvement, to be described. The number of patients with nasal and testicular involvement described in the literature is low. Creating awareness of this rare clinical condition is necessary, especially due to the very effective available treatment with corticosteroids and rituximab. | ||
650 | 4 | |a IgG4-related disease | |
650 | 4 | |a immunoglobulin G4 | |
650 | 4 | |a autoimmune | |
650 | 4 | |a pancreatitis | |
650 | 4 | |a orchitis | |
650 | 4 | |a nasal polyps | |
653 | 0 | |a Medicine | |
653 | 0 | |a R | |
700 | 0 | |a Darko Bogdanovic |e verfasserin |4 aut | |
700 | 0 | |a Kamran Mahmutyazicioglu |e verfasserin |4 aut | |
700 | 0 | |a Sam Ghazi |e verfasserin |4 aut | |
700 | 0 | |a Nikola Panic |e verfasserin |4 aut | |
700 | 0 | |a Eva Fjellgren |e verfasserin |4 aut | |
700 | 0 | |a Laila Hellkvist |e verfasserin |4 aut | |
700 | 0 | |a Tomas Thiel |e verfasserin |4 aut | |
700 | 0 | |a Anders Kjellman |e verfasserin |4 aut | |
700 | 0 | |a Nikolaos Kartalis |e verfasserin |4 aut | |
700 | 0 | |a Olof Danielsson |e verfasserin |4 aut | |
700 | 0 | |a Lara Dani |e verfasserin |4 aut | |
700 | 0 | |a J.-Matthias Löhr |e verfasserin |4 aut | |
700 | 0 | |a Miroslav Vujasinovic |e verfasserin |4 aut | |
773 | 0 | 8 | |i In |t Journal of Clinical Medicine |d MDPI AG, 2013 |g 12(2023), 6340, p 6340 |w (DE-627)DOAJ000006793 |x 20770383 |7 nnns |
773 | 1 | 8 | |g volume:12 |g year:2023 |g number:6340, p 6340 |
856 | 4 | 0 | |u https://doi.org/10.3390/jcm12196340 |z kostenfrei |
856 | 4 | 0 | |u https://doaj.org/article/bbebdeedc8374c8b9b043feacca9feed |z kostenfrei |
856 | 4 | 0 | |u https://www.mdpi.com/2077-0383/12/19/6340 |z kostenfrei |
856 | 4 | 2 | |u https://doaj.org/toc/2077-0383 |y Journal toc |z kostenfrei |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_DOAJ | ||
951 | |a AR | ||
952 | |d 12 |j 2023 |e 6340, p 6340 |