Interleukin-5 Antagonist Monoclonal Antibody Therapy Improves Symptoms and Reduces Steroid Dependence in Eosinophilic Myocarditis Patients

Eosinophilic myocarditis (EM) is a rare disease associated with significant morbidity and mortality. This case series follows the clinical courses of 3 patients with EM. The use of mepolizumab, an anti–interleukin-5 monoclonal antibody, as an adjunctive treatment was associated with stabilization of cardiac function and improved long-term outcomes..

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:29

Enthalten in:

JACC: Case Reports - 29(2024), 7, Seite 102267-

Sprache:

Englisch

Beteiligte Personen:

Vincenzo Trovato, MD [VerfasserIn]
Ashlee Asada, MD [VerfasserIn]
Lynn Fussner, MD [VerfasserIn]
Casey Curtis, MD [VerfasserIn]
Rami Kahwash, MD [VerfasserIn]

Links:

doi.org [kostenfrei]
doaj.org [kostenfrei]
www.sciencedirect.com [kostenfrei]
Journal toc [kostenfrei]

Themen:

Diseases of the circulatory (Cardiovascular) system
Eosinophilic myocarditis
Interleukin-5
Myocarditis
Reduced ejection fraction
Steroid-sparing

doi:

10.1016/j.jaccas.2024.102267

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

DOAJ091684250