Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studiesResearch in context
Summary: Background: The biological aging process can be modified through lifestyle interventions to prevent age-related diseases and extend healthspan. However, evidence from population-based studies on whether tea consumption could delay the biological aging process in humans remains limited. Methods: This study included 7931 participants aged 30–79 years from the China Multi-Ethnic Cohort (CMEC) Study and 5998 participants aged 37–73 years from the UK Biobank (UKB) who participated in both the baseline and first follow-up surveys. Tea consumption information was collected through questionnaires. Biological age (BA) acceleration was calculated using clinical biomarkers and anthropometric measurements based on the Klemera Doubal method (KDM). Change-to-change analyses were performed to estimate the associations between changes in tea consumption status and changes in BA acceleration using multiple linear models. Follow-up adjusted for baseline analyses were further conducted to examine the prospective exposure-response relationship between tea consumption and BA acceleration among individuals with constant tea consumption status. Findings: During a median follow-up of 1.98 (1.78, 2.16) years in the CMEC and 4.50 (3.92, 5.00) years in the UKB, tea consumption was consistently associated with attenuated BA acceleration in both cohorts. Transitioning from nondrinking to tea-drinking was associated with decreased BA acceleration (CMEC: β = −0.319, 95% CI: −0.620 to −0.017 years; UKB: β = −0.267, 95% CI: −0.831 to 0.297 years) compared to consistent nondrinking. Even stronger associations were found in consistent tea drinkers. The exposure-response relationship suggested that consuming around 3 cups of tea or 6–8 g of tea leaves per day may offer the most evident anti-aging benefits. Interpretation: Tea consumption was associated with attenuated BA acceleration measured by KDM, especially for consistent tea drinkers with moderate consumption. Our findings highlight the potential role of tea in developing nutrition-oriented anti-aging interventions and guiding healthy aging policies. Funding: National Natural Science Foundation of China (Grant No. 82273740)..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:42 |
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| Enthalten in: |
The Lancet Regional Health. Western Pacific - 42(2024), Seite 100955- |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yi Xiang [VerfasserIn] |
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| Links: |
doi.org [kostenfrei] |
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| Themen: |
Biological aging |
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| doi: |
10.1016/j.lanwpc.2023.100955 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
DOAJ091543460 |
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| 245 | 1 | 0 | |a Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studiesResearch in context |
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| 520 | |a Summary: Background: The biological aging process can be modified through lifestyle interventions to prevent age-related diseases and extend healthspan. However, evidence from population-based studies on whether tea consumption could delay the biological aging process in humans remains limited. Methods: This study included 7931 participants aged 30–79 years from the China Multi-Ethnic Cohort (CMEC) Study and 5998 participants aged 37–73 years from the UK Biobank (UKB) who participated in both the baseline and first follow-up surveys. Tea consumption information was collected through questionnaires. Biological age (BA) acceleration was calculated using clinical biomarkers and anthropometric measurements based on the Klemera Doubal method (KDM). Change-to-change analyses were performed to estimate the associations between changes in tea consumption status and changes in BA acceleration using multiple linear models. Follow-up adjusted for baseline analyses were further conducted to examine the prospective exposure-response relationship between tea consumption and BA acceleration among individuals with constant tea consumption status. Findings: During a median follow-up of 1.98 (1.78, 2.16) years in the CMEC and 4.50 (3.92, 5.00) years in the UKB, tea consumption was consistently associated with attenuated BA acceleration in both cohorts. Transitioning from nondrinking to tea-drinking was associated with decreased BA acceleration (CMEC: β = −0.319, 95% CI: −0.620 to −0.017 years; UKB: β = −0.267, 95% CI: −0.831 to 0.297 years) compared to consistent nondrinking. Even stronger associations were found in consistent tea drinkers. The exposure-response relationship suggested that consuming around 3 cups of tea or 6–8 g of tea leaves per day may offer the most evident anti-aging benefits. Interpretation: Tea consumption was associated with attenuated BA acceleration measured by KDM, especially for consistent tea drinkers with moderate consumption. Our findings highlight the potential role of tea in developing nutrition-oriented anti-aging interventions and guiding healthy aging policies. Funding: National Natural Science Foundation of China (Grant No. 82273740). | ||
| 650 | 4 | |a Biological aging | |
| 650 | 4 | |a Tea consumption | |
| 650 | 4 | |a Change-to-change analysis | |
| 650 | 4 | |a Follow-up adjusted for baseline analysis | |
| 650 | 4 | |a Exposure-response relationship | |
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| 700 | 0 | |a Hao Xu |e verfasserin |4 aut | |
| 700 | 0 | |a Hongxiang Chen |e verfasserin |4 aut | |
| 700 | 0 | |a Dan Tang |e verfasserin |4 aut | |
| 700 | 0 | |a Zitong Huang |e verfasserin |4 aut | |
| 700 | 0 | |a Yuan Zhang |e verfasserin |4 aut | |
| 700 | 0 | |a Zhenghong Wang |e verfasserin |4 aut | |
| 700 | 0 | |a Ziyun Wang |e verfasserin |4 aut | |
| 700 | 0 | |a Yangla |e verfasserin |4 aut | |
| 700 | 0 | |a Mingming Han |e verfasserin |4 aut | |
| 700 | 0 | |a Jianzhong Yin |e verfasserin |4 aut | |
| 700 | 0 | |a Xiong Xiao |e verfasserin |4 aut | |
| 700 | 0 | |a Xing Zhao |e verfasserin |4 aut | |
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