Medication and Dose Optimization in Extracorporeal Membrane Oxygenation
Extracorporeal membrane oxygenation (ECMO) increases circulating volume of distribution, leading to capillary leakage and temporarily altering renal function. Therefore, this may affect pharmacokinetics. In this review, factors affecting pharmacokinetics and pharmacodynamics in veno-arterial and venovenous ECMO, the causes of drug sequestration that may occur in the ECMO circuit, the effects of physicochemical parameters of drugs in the ECMO circuit, and ECMO variable dose optimization have been reviewed from the studies in the current literature. Data reported on the limitations, indications and complications of ECMO are also mentioned. The limited use of ECMO in the coronavirus disease-2019 pandemic, its use in reported cases, and which symptoms it is usually used to support the treatment of are described..
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2024 |
---|---|
Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:22 |
---|---|
Enthalten in: |
Türk Yoğun Bakim Derneği Dergisi - 22(2024), 1, Seite 14 |
Sprache: |
Englisch ; Türkisch |
---|
Beteiligte Personen: |
Nadir Yalçın [VerfasserIn] |
---|
Links: |
doi.org [kostenfrei] |
---|
Themen: |
Dose adjustment |
---|
doi: |
10.4274/tybd.galenos.2024.45822 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
DOAJ091285259 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | DOAJ091285259 | ||
003 | DE-627 | ||
005 | 20240414033452.0 | ||
007 | cr uuu---uuuuu | ||
008 | 240412s2024 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.4274/tybd.galenos.2024.45822 |2 doi | |
035 | |a (DE-627)DOAJ091285259 | ||
035 | |a (DE-599)DOAJ784cabefdd1e422d877b538cbb1aa021 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng |a tur | ||
050 | 0 | |a RC31-1245 | |
050 | 0 | |a RC86-88.9 | |
100 | 0 | |a Nadir Yalçın |e verfasserin |4 aut | |
245 | 1 | 0 | |a Medication and Dose Optimization in Extracorporeal Membrane Oxygenation |
264 | 1 | |c 2024 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
520 | |a Extracorporeal membrane oxygenation (ECMO) increases circulating volume of distribution, leading to capillary leakage and temporarily altering renal function. Therefore, this may affect pharmacokinetics. In this review, factors affecting pharmacokinetics and pharmacodynamics in veno-arterial and venovenous ECMO, the causes of drug sequestration that may occur in the ECMO circuit, the effects of physicochemical parameters of drugs in the ECMO circuit, and ECMO variable dose optimization have been reviewed from the studies in the current literature. Data reported on the limitations, indications and complications of ECMO are also mentioned. The limited use of ECMO in the coronavirus disease-2019 pandemic, its use in reported cases, and which symptoms it is usually used to support the treatment of are described. | ||
650 | 4 | |a extracorporeal membrane oxygenation | |
650 | 4 | |a ecmo circuit | |
650 | 4 | |a drug | |
650 | 4 | |a pharmacokinetics | |
650 | 4 | |a pharmacodynamics | |
650 | 4 | |a dose adjustment | |
653 | 0 | |a Medicine | |
653 | 0 | |a R | |
653 | 0 | |a Internal medicine | |
653 | 0 | |a Medical emergencies. Critical care. Intensive care. First aid | |
700 | 0 | |a Mehmet Akkaya |e verfasserin |4 aut | |
700 | 0 | |a Kutay Demirkan |e verfasserin |4 aut | |
773 | 0 | 8 | |i In |t Türk Yoğun Bakim Derneği Dergisi |d Galenos Yayinevi, 2015 |g 22(2024), 1, Seite 14 |w (DE-627)DOAJ000019054 |x 2147267X |7 nnns |
773 | 1 | 8 | |g volume:22 |g year:2024 |g number:1 |g pages:14 |
856 | 4 | 0 | |u https://doi.org/10.4274/tybd.galenos.2024.45822 |z kostenfrei |
856 | 4 | 0 | |u https://doaj.org/article/784cabefdd1e422d877b538cbb1aa021 |z kostenfrei |
856 | 4 | 0 | |u http://www.turkishjic.org/archives/archive-detail/article-preview/medication-and-dose-optimization-in-extracorporeal/64666 |z kostenfrei |
856 | 4 | 2 | |u https://doaj.org/toc/2146-6416 |y Journal toc |z kostenfrei |
856 | 4 | 2 | |u https://doaj.org/toc/2147-267X |y Journal toc |z kostenfrei |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_DOAJ | ||
951 | |a AR | ||
952 | |d 22 |j 2024 |e 1 |h 14 |