Polymeric Materials for Hemostatic Wound Healing

Hemorrhage is one of the greatest threats to life on the battlefield, accounting for 50% of total deaths. Nearly 86% of combat deaths occur within the first 30 min after wounding. While external wound injuries can be treated mostly using visual inspection, abdominal or internal hemorrhages are more challenging to treat with regular hemostatic dressings because of deep wounds and points of injury that cannot be located properly. The need to treat trauma wounds from limbs, abdomen, liver, stomach, colon, spleen, arterial, venous, and/or parenchymal hemorrhage accompanied by severe bleeding requires an immediate solution that the first responders can apply to reduce rapid exsanguinations from external wounds, including in military operations. This necessitates the development of a unique, easy-to-use, FDA-approved hemostatic treatment that can deliver the agent in less than 30 s and stop bleeding within the first 1 to 2 min at the point of injury without application of manual pressure on the wounded area..

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:13

Enthalten in:

Pharmaceutics - 13(2021), 12, p 2127

Sprache:

Englisch

Beteiligte Personen:

Suvash Ghimire [VerfasserIn]
Pritha Sarkar [VerfasserIn]
Kasey Rigby [VerfasserIn]
Aditya Maan [VerfasserIn]
Santanu Mukherjee [VerfasserIn]
Kaitlyn E. Crawford [VerfasserIn]
Kausik Mukhopadhyay [VerfasserIn]

Links:

doi.org [kostenfrei]
doaj.org [kostenfrei]
www.mdpi.com [kostenfrei]
Journal toc [kostenfrei]

Themen:

Blood
Hemostasis
Metals
Nanoparticles
Pharmacy and materia medica
Polymer
Wound

doi:

10.3390/pharmaceutics13122127

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

DOAJ084756438