Detection and Genotypic Analysis of <i<Anaplasma bovis</i< and <i<A. phagocytophilum</i< in Horse Blood and Lung Tissue
A clinical case of <i<Anaplasma bovis</i< was reported for the first time in our previous study (2019) in a horse, a nondefinitive host. Although <i<A. bovis</i< is a ruminant and not a zoonotic pathogen, it is responsible for persistent infections in horses. In this follow-up study, the prevalence of <i<Anaplasma</i< spp., including <i<A. bovis</i<, was assessed in horse blood and lung tissue samples to fully understand <i<Anaplasma</i< spp. pathogen distribution and the potential risk factors of infection. Among 1696 samples, including 1433 blood samples from farms nationwide and 263 lung tissue samples from horse abattoirs on Jeju Island, a total of 29 samples (1.7%) tested positive for <i<A. bovis</i< and 31 (1.8%) samples tested positive for <i<A. phagocytophilum</i<, as determined by 16S rRNA nucleotide sequencing and restriction fragment length polymorphism. This study is the first to detect <i<A. bovis</i< infection in horse lung tissue samples. Further studies are needed to clarify the comparison of sample types within cohorts. Although the clinical significance of <i<Anaplasma</i< infection was not evaluated in this study, our results emphasize the need to clarify the host tropism and genetic divergence of <i<Anaplasma</i< to enable the development of effective prevention and control measures through broad epidemiological studies..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:24 |
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| Enthalten in: |
International Journal of Molecular Sciences - 24(2023), 4, p 3239 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Min-Goo Seo [VerfasserIn] |
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| Links: |
doi.org [kostenfrei] |
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| Themen: |
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| doi: |
10.3390/ijms24043239 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
DOAJ080263534 |
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| 520 | |a A clinical case of <i<Anaplasma bovis</i< was reported for the first time in our previous study (2019) in a horse, a nondefinitive host. Although <i<A. bovis</i< is a ruminant and not a zoonotic pathogen, it is responsible for persistent infections in horses. In this follow-up study, the prevalence of <i<Anaplasma</i< spp., including <i<A. bovis</i<, was assessed in horse blood and lung tissue samples to fully understand <i<Anaplasma</i< spp. pathogen distribution and the potential risk factors of infection. Among 1696 samples, including 1433 blood samples from farms nationwide and 263 lung tissue samples from horse abattoirs on Jeju Island, a total of 29 samples (1.7%) tested positive for <i<A. bovis</i< and 31 (1.8%) samples tested positive for <i<A. phagocytophilum</i<, as determined by 16S rRNA nucleotide sequencing and restriction fragment length polymorphism. This study is the first to detect <i<A. bovis</i< infection in horse lung tissue samples. Further studies are needed to clarify the comparison of sample types within cohorts. Although the clinical significance of <i<Anaplasma</i< infection was not evaluated in this study, our results emphasize the need to clarify the host tropism and genetic divergence of <i<Anaplasma</i< to enable the development of effective prevention and control measures through broad epidemiological studies. | ||
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