The Effect of Trace Elements in the Development of Ascending Aorta Aneurysm
INTRODUCTION: Ascending aorta aneurysm is a serious condition with an undetermined pathophysiology. Trace elements are essential for the effective performance of the body's multiple systems, including the immune system, and relevant information to inflammation and infections. Since inflammation may contribute to the etiology of ascending aortic aneurysm, we investigated whether trace element alterations associated with inflammation occur in blood and tissue samples over the course of the condition. METHODS: We compared 32 individuals who underwent coronary artery bypass grafting and 23 patients who underwent surgery for an ascending aortic aneurysm. During surgery, samples of the ascending aorta's anterior portion were removed from the aortic wall. The tissue's iron (Fe), copper (Cu), and zinc (Zn) levels were measured. RESULTS: There were no statisticaly significant differences between the groups in the Zn averages of the cases divided by groups(p>0.05). Individual Cu mean values of the study group were statistically significantly lower than those of the control group (p <0.001). The mean Fe levels of the participants in the study group were identified to be statistically substantially higher than those of the control group (p <0.05). DISCUSSION AND CONCLUSION: In this study, we aimed to find out more about the relationship between changes in the levels of trace elements in the tissue of the ascending aorta and aneurysm development. We believe that changes in trace element levels may involve a role in the progression of aortic aneurysms..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
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| Enthalten in: |
Van Tıp Dergisi - 30(2023), 1, Seite 66-71 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sinan Gocer [VerfasserIn] |
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| Links: |
doi.org [kostenfrei] |
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| Themen: |
Ascending aorta aneurysm |
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| doi: |
10.5505/vtd.2023.30676 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
DOAJ080173608 |
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| 520 | |a INTRODUCTION: Ascending aorta aneurysm is a serious condition with an undetermined pathophysiology. Trace elements are essential for the effective performance of the body's multiple systems, including the immune system, and relevant information to inflammation and infections. Since inflammation may contribute to the etiology of ascending aortic aneurysm, we investigated whether trace element alterations associated with inflammation occur in blood and tissue samples over the course of the condition. METHODS: We compared 32 individuals who underwent coronary artery bypass grafting and 23 patients who underwent surgery for an ascending aortic aneurysm. During surgery, samples of the ascending aorta's anterior portion were removed from the aortic wall. The tissue's iron (Fe), copper (Cu), and zinc (Zn) levels were measured. RESULTS: There were no statisticaly significant differences between the groups in the Zn averages of the cases divided by groups(p>0.05). Individual Cu mean values of the study group were statistically significantly lower than those of the control group (p <0.001). The mean Fe levels of the participants in the study group were identified to be statistically substantially higher than those of the control group (p <0.05). DISCUSSION AND CONCLUSION: In this study, we aimed to find out more about the relationship between changes in the levels of trace elements in the tissue of the ascending aorta and aneurysm development. We believe that changes in trace element levels may involve a role in the progression of aortic aneurysms. | ||
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