The epidemiological and radiographical characteristics of asymptomatic infections with the novel coronavirus (COVID-19): A systematic review and meta-analysis
Objectives: The role of asymptomatic infections in the transmission of COVID-19 have drawn considerable attention. Here, we performed a meta-analysis to summarize the epidemiological and radiographical characteristics of asymptomatic infections associated with COVID-19. Methods: Data on the epidemiological and radiographical characteristics of asymptomatic infections were extracted from the existing literature. Pooled proportions with 95% confidence intervals were then calculated using a random effects model. Results: A total of 104 studies involving 20,152 cases were included. The proportion of asymptomatic individuals among those with COVID-19 was 13.34% (10.86%–16.29%), among which presymptomatic and covert infections accounted for 7.64% (4.02%–14.04%) and 8.44% (5.12%–13.62%), respectively. The proportions of asymptomatic infections among infected children and healthcare workers were 32.24% (23.08%–42.13%) and 36.96% (18.51%–60.21%), respectively. The proportion of asymptomatic infections was significantly higher after 2020/02/29 than before (33.53% vs 10.19%) and in non-Asian regions than in Asia (28.76% vs 11.54%). The median viral shedding duration of asymptomatic infections was 14.14 days (11.25–17.04). A total of 47.62% (31.13%–72.87%) of asymptomatic infections showed lung abnormalities, especially ground-glass opacity (41.11% 19.7%–85.79%). Conclusions: Asymptomatic infections were more commonly found in infected children and healthcare workers and increased after 2020/02/29 and in non-Asian regions. Chest radiographical imaging could be conducive to the early identification of asymptomatic infections..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:104 |
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| Enthalten in: |
International Journal of Infectious Diseases - 104(2021), Seite 458-464 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Can Chen [VerfasserIn] |
|---|
| Links: |
doi.org [kostenfrei] |
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| Themen: |
Asymptomatic |
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| doi: |
10.1016/j.ijid.2021.01.017 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
DOAJ06879049X |
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| 245 | 1 | 4 | |a The epidemiological and radiographical characteristics of asymptomatic infections with the novel coronavirus (COVID-19): A systematic review and meta-analysis |
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| 520 | |a Objectives: The role of asymptomatic infections in the transmission of COVID-19 have drawn considerable attention. Here, we performed a meta-analysis to summarize the epidemiological and radiographical characteristics of asymptomatic infections associated with COVID-19. Methods: Data on the epidemiological and radiographical characteristics of asymptomatic infections were extracted from the existing literature. Pooled proportions with 95% confidence intervals were then calculated using a random effects model. Results: A total of 104 studies involving 20,152 cases were included. The proportion of asymptomatic individuals among those with COVID-19 was 13.34% (10.86%–16.29%), among which presymptomatic and covert infections accounted for 7.64% (4.02%–14.04%) and 8.44% (5.12%–13.62%), respectively. The proportions of asymptomatic infections among infected children and healthcare workers were 32.24% (23.08%–42.13%) and 36.96% (18.51%–60.21%), respectively. The proportion of asymptomatic infections was significantly higher after 2020/02/29 than before (33.53% vs 10.19%) and in non-Asian regions than in Asia (28.76% vs 11.54%). The median viral shedding duration of asymptomatic infections was 14.14 days (11.25–17.04). A total of 47.62% (31.13%–72.87%) of asymptomatic infections showed lung abnormalities, especially ground-glass opacity (41.11% 19.7%–85.79%). Conclusions: Asymptomatic infections were more commonly found in infected children and healthcare workers and increased after 2020/02/29 and in non-Asian regions. Chest radiographical imaging could be conducive to the early identification of asymptomatic infections. | ||
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Asymptomatic | |
| 650 | 4 | |a Presymptomatic | |
| 650 | 4 | |a Covert infections | |
| 650 | 4 | |a Epidemiological characteristics | |
| 650 | 4 | |a Radiographical findings | |
| 653 | 0 | |a Infectious and parasitic diseases | |
| 700 | 0 | |a Changtai Zhu |e verfasserin |4 aut | |
| 700 | 0 | |a Danying Yan |e verfasserin |4 aut | |
| 700 | 0 | |a Hongchao Liu |e verfasserin |4 aut | |
| 700 | 0 | |a Danfeng Li |e verfasserin |4 aut | |
| 700 | 0 | |a Yuqing Zhou |e verfasserin |4 aut | |
| 700 | 0 | |a Xiaofang Fu |e verfasserin |4 aut | |
| 700 | 0 | |a Jie Wu |e verfasserin |4 aut | |
| 700 | 0 | |a Cheng Ding |e verfasserin |4 aut | |
| 700 | 0 | |a Guo Tian |e verfasserin |4 aut | |
| 700 | 0 | |a Lei Lan |e verfasserin |4 aut | |
| 700 | 0 | |a Xiaoxiao Liu |e verfasserin |4 aut | |
| 700 | 0 | |a Chenyang Huang |e verfasserin |4 aut | |
| 700 | 0 | |a Robert Hecht |e verfasserin |4 aut | |
| 700 | 0 | |a Lanjuan Li |e verfasserin |4 aut | |
| 700 | 0 | |a Shigui Yang |e verfasserin |4 aut | |
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