Low serum levels of vitamin D significantly increase the risk of death in older adults with hip fractures: a prospective cohort
ABSTRACT Objective: to evaluate the relationship between 25(OH)D3 levels and fatal outcome in patients over 60 years of age undergoing surgical repair of hip fractures. Methods: prospective cohort of patients undergoing surgical repair of hip fractures. At admission, 25(OH)D3 levels were measured, among other parameters. Patients were followed for at least 1 year, and incident mortality was recorded. Results: 209 patients were included in the study, with a mean age of 79.5 ± 7.6 years among survivors and 80.7 ± 8.2 years among those who died in the first postoperative year (p=0.346). The 25(OH)D3 levels of survivors were significantly higher than those of patients who died (p=0.003). After adjusting for confounding variables, 25(OH)D3 levels below 12.5ng/mL were significant risk factors regardless of mortality (adjusted OR: 7.6; 95% CI: 2.35 to 24.56). Conclusions: our data show that serum 25(OH)D3 levels below 12.5ng/mL significantly and independently increased the risk of mortality in the first year after surgical repair of low-energy hip fracture in patients over 60 years of age in the geographic region where this study was conducted. Low albumin also showed a significant association with mortality in these patients. All other factors had no significant associations..
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2022 |
---|---|
Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:49 |
---|---|
Enthalten in: |
Revista do Colégio Brasileiro de Cirurgiões - 49(2022) |
Sprache: |
Englisch ; Spanisch ; Portugiesisch |
---|
Beteiligte Personen: |
MARCELO TEODORO EZEQUIEL GUERRA [VerfasserIn] |
---|
Links: |
doi.org [kostenfrei] |
---|
Themen: |
---|
doi: |
10.1590/0100-6991e-20223054 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
DOAJ063723573 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | DOAJ063723573 | ||
003 | DE-627 | ||
005 | 20230502125222.0 | ||
007 | cr uuu---uuuuu | ||
008 | 230228s2022 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1590/0100-6991e-20223054 |2 doi | |
035 | |a (DE-627)DOAJ063723573 | ||
035 | |a (DE-599)DOAJ443d776d342d4d688c2b6fd7cc7464d4 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng |a spa |a por | ||
050 | 0 | |a RD1-811 | |
100 | 0 | |a MARCELO TEODORO EZEQUIEL GUERRA |e verfasserin |4 aut | |
245 | 1 | 0 | |a Low serum levels of vitamin D significantly increase the risk of death in older adults with hip fractures: a prospective cohort |
264 | 1 | |c 2022 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
520 | |a ABSTRACT Objective: to evaluate the relationship between 25(OH)D3 levels and fatal outcome in patients over 60 years of age undergoing surgical repair of hip fractures. Methods: prospective cohort of patients undergoing surgical repair of hip fractures. At admission, 25(OH)D3 levels were measured, among other parameters. Patients were followed for at least 1 year, and incident mortality was recorded. Results: 209 patients were included in the study, with a mean age of 79.5 ± 7.6 years among survivors and 80.7 ± 8.2 years among those who died in the first postoperative year (p=0.346). The 25(OH)D3 levels of survivors were significantly higher than those of patients who died (p=0.003). After adjusting for confounding variables, 25(OH)D3 levels below 12.5ng/mL were significant risk factors regardless of mortality (adjusted OR: 7.6; 95% CI: 2.35 to 24.56). Conclusions: our data show that serum 25(OH)D3 levels below 12.5ng/mL significantly and independently increased the risk of mortality in the first year after surgical repair of low-energy hip fracture in patients over 60 years of age in the geographic region where this study was conducted. Low albumin also showed a significant association with mortality in these patients. All other factors had no significant associations. | ||
650 | 4 | |a Albumins | |
650 | 4 | |a Aged | |
650 | 4 | |a Mortality | |
650 | 4 | |a Nutritional Status | |
650 | 4 | |a Vitamin D | |
653 | 0 | |a Surgery | |
700 | 0 | |a MARIO WAGNER |e verfasserin |4 aut | |
700 | 0 | |a ALFONSO VARGAS |e verfasserin |4 aut | |
700 | 0 | |a CARLOS ROBERTO GALIA |e verfasserin |4 aut | |
773 | 0 | 8 | |i In |t Revista do Colégio Brasileiro de Cirurgiões |d Colégio Brasileiro de Cirurgiões, 2005 |g 49(2022) |w (DE-627)DOAJ00002158X |x 18094546 |7 nnns |
773 | 1 | 8 | |g volume:49 |g year:2022 |
856 | 4 | 0 | |u https://doi.org/10.1590/0100-6991e-20223054 |z kostenfrei |
856 | 4 | 0 | |u https://doaj.org/article/443d776d342d4d688c2b6fd7cc7464d4 |z kostenfrei |
856 | 4 | 0 | |u http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912022000100209&tlng=en |z kostenfrei |
856 | 4 | 0 | |u http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912022000100209&tlng=pt |z kostenfrei |
856 | 4 | 2 | |u https://doaj.org/toc/1809-4546 |y Journal toc |z kostenfrei |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_DOAJ | ||
912 | |a SSG-OLC-PHA | ||
951 | |a AR | ||
952 | |d 49 |j 2022 |