Relation of neutrophil/lymphocyte ratio with the presence and severity of coronary artery ectasia

Objectives: It has been shown that the neutrophil to lymphocyte ratio (N/L ratio) is associated with cardiovascular events and mortality. In this study, we investigated the N/L ratio in patients with coronary artery ectasia (CAE). Study design: Fifty patients diagnosed with CAE using coronary angiography were included in the study (29 male, 21 female; mean age, 51.1+-7.1 years). The control group consisted of 28 patients who had normal coronary arteries as determined by coronary angiography (16 male, 12 female; mean age, 49.5+-9.4 years). Basal characteristics were recorded. The number of ectatic segments was noted. Hematologic parameters were measured and the N/L ratio was calculated. Results: The N/L ratio was significantly higher in the CAE group compared with control group (median [25-75% percentile] 2.2 [1.6-3.0] vs. 1.8 [1.4-2.0], p=0.014, respectively). The Spearman correlation analysis demonstrated that the N/L ratio positively correlated with number of ectatic segments (r=0.35; p<0.002). Multivariable logistic regression analysis showed an independent relationship between CAE and the N/L ratio (odds ratio 2.674, 95% confidence interval 1.184-6.039, p=0.018). Conclusion: The N/L ratio is higher in patients with CAE. This ratio is related to presence and severity of CAE..

Medienart:

E-Artikel

Erscheinungsjahr:

2013

Erschienen:

2013

Enthalten in:

Zur Gesamtaufnahme - volume:41

Enthalten in:

Türk Kardiyoloji Derneği Arşivi - 41(2013), 3, Seite 185-190

Sprache:

Englisch ; Türkisch

Beteiligte Personen:

S. Selim Ayhan [VerfasserIn]
Serkan Öztürk [VerfasserIn]
Alim Erdem [VerfasserIn]
Mehmet Fatih Özlü [VerfasserIn]
Mehmet Özyaşar [VerfasserIn]
Kemalettin Erdem [VerfasserIn]
Mehmet Yazıcı [VerfasserIn]

Links:

doi.org [kostenfrei]
doaj.org [kostenfrei]
jag.journalagent.com [kostenfrei]
Journal toc [kostenfrei]

Themen:

Coronary aneurysm; coronary angiography; coronary vessels/pathology; lymphocyte count; neutrophils; risk assessment.
Dilatation
Diseases of the circulatory (Cardiovascular) system
Internal medicine
Medicine
Pathologic/etiology
R

doi:

10.5543/tkda.2013.83030

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

DOAJ059035919