Role of Gender in Improvement of Depressive Symptoms Among Patients Undergoing Cervical Spine Procedures

Objective There is a scarcity of research evaluating gender differences in depressive symptoms among patients undergoing cervical surgery. This study investigated gender differences with regard to depressive symptom severity, measured by Patient Health Questionnaire-9 (PHQ-9), in patients following anterior cervical discectomy and fusion (ACDF) or artificial disc replacement (ADR). Methods A prospectively maintained surgical registry was retrospectively reviewed for eligible spine surgeries. Depressive symptom severity was evaluated by PHQ-9 at both preand postoperative timepoints (e.g. , 6 weeks, 12 weeks, 6 months, 1 year, and 2 years). A chi-square test and Student t-test evaluated differences between the gender for demographic and operative variables where appropriate. Differences between the gender subgroup mean PHQ-9 scores were assessed using a t-test pre- and postoperatively (e.g. , 6 weeks, 12 weeks, 6 months, and 1 year) and a paired t-test was used to assess differences from preoperative scores at each postoperative time point. Results A total of 170 subjects underwent 125 ACDFs and 45 ADRs. Both pre- and postoperative timepoints demonstrated no significant differences between mean PHQ-9 scores by gender. Female patients demonstrated statistically significant improvement in PHQ-9 scores at 6 weeks, and 12 weeks, but not through 2 years. Male patients demonstrated statistically significant improvement in PHQ-9 scores at 6 weeks, 12 weeks, 6 months, 1 year, and 2 years. Conclusion Although there were no significant differences between mean PHQ-9 score between the genders, there was a difference in magnitude of improvement. Females had a significant improvement in depressive symptom severity over baseline at the 6- and 12-week timepoints only, whereas males had significant improvement through 2 years postoperatively..

Medienart:	E-Artikel

Erscheinungsjahr:	2021
Erschienen:	2021

Enthalten in:	Zur Gesamtaufnahme - volume:18
Enthalten in:	Neurospine - 18(2021), 1, Seite 217-225

Sprache:	Englisch

Beteiligte Personen:	Elliot D.K. Cha [VerfasserIn] Conor P. Lynch [VerfasserIn] James M. Parrish [VerfasserIn] Nathaniel W. Jenkins [VerfasserIn] Cara E. Geoghegan [VerfasserIn] Caroline N. Jadczak [VerfasserIn] Shruthi Mohan [VerfasserIn] Kern Singh [VerfasserIn]

Links:	doi.org [kostenfrei] doaj.org [kostenfrei] www.e-neurospine.org [kostenfrei] Journal toc [kostenfrei] Journal toc [kostenfrei]

Themen:	Anterior cervical discectomy and fusion Artificial disc replacement Depression Gender Neurology. Diseases of the nervous system Patient health questionnaire-9

doi:	10.14245/ns.2040610.305

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	DOAJ050302108