COVID-19 Therapeutic Options Under Investigation

Since its emergence in China in December 2019, COVID-19 has quickly spread around the globe causing a pandemic. Vaccination or the development of herd immunity seems the only way to slow down the spread of the virus; however, both are not achievable in the near future. Therefore, effective treatments to mitigate the burden of this pandemic and reduce mortality rates are urgently needed. Preclinical and clinical studies of potential antiviral and immunomodulatory compounds and molecules to identify safe and efficacious therapeutics for COVID-19 are ongoing. Two compounds, remdesivir, and dexamethasone have been so far shown to reduce COVID-19–associated death. Here, we provide a review of the potential therapeutic agents being considered for the treatment and management of COVID-19 patients..

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:11

Enthalten in:

Frontiers in Pharmacology - 11(2020)

Sprache:

Englisch

Beteiligte Personen:

Malak Kaddoura [VerfasserIn]
Malak Kaddoura [VerfasserIn]
Malak AlIbrahim [VerfasserIn]
Malak AlIbrahim [VerfasserIn]
Ghina Hijazi [VerfasserIn]
Ghina Hijazi [VerfasserIn]
Nadia Soudani [VerfasserIn]
Nadia Soudani [VerfasserIn]
Amani Audi [VerfasserIn]
Amani Audi [VerfasserIn]
Habib Alkalamouni [VerfasserIn]
Habib Alkalamouni [VerfasserIn]
Salame Haddad [VerfasserIn]
Salame Haddad [VerfasserIn]
Ali Eid [VerfasserIn]
Hassan Zaraket [VerfasserIn]
Hassan Zaraket [VerfasserIn]

Links:

doi.org [kostenfrei]
doaj.org [kostenfrei]
www.frontiersin.org [kostenfrei]
Journal toc [kostenfrei]

Themen:

Adjunctive therapy
Antivirals
COVID-19
SARS-CoV-2
Therapeutics
Therapeutics. Pharmacology

doi:

10.3389/fphar.2020.01196

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

DOAJ046273247