Modelling of retinal vasculature based on genetically tuned parametric L-system
Structures of retinal blood vessels are of great importance in diagnosis and treatment of diseases that affect the eyes. Parametric Lindenmayer system (L-system) is one of the powerful rule-based methods that has a great capability for generating tree-like structures using simple rewriting rules. In this study, a novel framework, which can be used to model the retinal vasculature based on available images, has been proposed. This framework presents a solution to special instance of a general open problem, the L-system inverse problem, in which L-system rules should be obtained based on images representing a particular tree-like structure. In this study, genetic algorithm with a novel objective function based on feature matching and an L-system grammar comparison has been used along with nonlinear regression to solve the parametric L-system inverse problem. The resulting L-system growth rules have been employed to predict inaccessible vascular branches. Graphical and quantitative comparison between model results and target structures of different case studies reveals that the proposed framework can be used to generate the structure of retinal blood vessels accurately. Even in the cases lacking sufficient image data, it can provide acceptable predictions..
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2018 |
|---|---|
| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:5 |
|---|---|
| Enthalten in: |
Royal Society Open Science - 5(2018), 5 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Seyed Mohammad Ali Aghamirmohammadali [VerfasserIn] |
|---|
| Links: |
doi.org [kostenfrei] |
|---|
| Themen: |
L-system inverse problem |
|---|
| doi: |
10.1098/rsos.171639 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
DOAJ045981833 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | DOAJ045981833 | ||
| 003 | DE-627 | ||
| 005 | 20230308101503.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230227s2018 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1098/rsos.171639 |2 doi | |
| 035 | |a (DE-627)DOAJ045981833 | ||
| 035 | |a (DE-599)DOAJb52b55baaa0443f8900f7ef6a4e03ff2 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 0 | |a Seyed Mohammad Ali Aghamirmohammadali |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Modelling of retinal vasculature based on genetically tuned parametric L-system |
| 264 | 1 | |c 2018 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Structures of retinal blood vessels are of great importance in diagnosis and treatment of diseases that affect the eyes. Parametric Lindenmayer system (L-system) is one of the powerful rule-based methods that has a great capability for generating tree-like structures using simple rewriting rules. In this study, a novel framework, which can be used to model the retinal vasculature based on available images, has been proposed. This framework presents a solution to special instance of a general open problem, the L-system inverse problem, in which L-system rules should be obtained based on images representing a particular tree-like structure. In this study, genetic algorithm with a novel objective function based on feature matching and an L-system grammar comparison has been used along with nonlinear regression to solve the parametric L-system inverse problem. The resulting L-system growth rules have been employed to predict inaccessible vascular branches. Graphical and quantitative comparison between model results and target structures of different case studies reveals that the proposed framework can be used to generate the structure of retinal blood vessels accurately. Even in the cases lacking sufficient image data, it can provide acceptable predictions. | ||
| 650 | 4 | |a retinal vasculature | |
| 650 | 4 | |a parametric l-system | |
| 650 | 4 | |a l-system inverse problem | |
| 650 | 4 | |a mathematical morphology | |
| 653 | 0 | |a Science | |
| 653 | 0 | |a Q | |
| 700 | 0 | |a Ramin Bozorgmehry Boozarjomehry |e verfasserin |4 aut | |
| 700 | 0 | |a Mohammad Abdekhodaie |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i In |t Royal Society Open Science |d The Royal Society, 2015 |g 5(2018), 5 |w (DE-627)DOAJ000028932 |x 20545703 |7 nnns |
| 773 | 1 | 8 | |g volume:5 |g year:2018 |g number:5 |
| 856 | 4 | 0 | |u https://doi.org/10.1098/rsos.171639 |z kostenfrei |
| 856 | 4 | 0 | |u https://doaj.org/article/b52b55baaa0443f8900f7ef6a4e03ff2 |z kostenfrei |
| 856 | 4 | 0 | |u https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171639 |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/2054-5703 |y Journal toc |z kostenfrei |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_DOAJ | ||
| 951 | |a AR | ||
| 952 | |d 5 |j 2018 |e 5 | ||