SERUM LEVEL OF SOME CYTOKINES IN CHILDREN 6-10 YEARS OLD WITH HIGH FREQUENCY OF ACUTE RESPIRATORY INFECTIONS
Objective: improved diagnosis of immune disorders in children aged 6-10 years old, who are often ill od upper respiratory tract infections (URTI), on the basis of these data, further investigation of serum equalities of cytokines, a way of diagnosing with indications in healthy children. Materials and methods. There were 60 children of 6 to 10 years of age, from which 2 groups were formed: 1). children who are often ill with URTI (n=30); 2). children, who do not get sick often URTI (n=30). Results. among children of 6-10 years of age, as often ill with URTI, the frequency of registration of high indications in place of interleukin-6 blood serum (by 53.3%, p<0.05), TNF (by 63.3%, p <0.05) and low indications for interleukin-10 (by 33.3%, p<0.05), it was established that there was a high probability (odds ratio) of an increase serum interleukin-6, TNF and a decrease in interleukin-10 as a reference value, it is associated with the presence of an increased incidence of URTI in children. Conclusion. in children aged 6-10 years, as they often fall ill with URTI, may tend to intensify pro-inflammation of the immune reactions, which still does not ensure a decrease in serious illness on URTI and unsafe side of the development of opportunistic diseases..
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2022 |
|---|---|
| Enthalten in: |
Сучасні медичні технології - (2022), 2(53), Seite 15-18 |
| Sprache: |
Englisch ; Ukrainisch |
|---|
| Beteiligte Personen: |
L. S. Ovcharenko [VerfasserIn] |
|---|
| Links: |
doi.org [kostenfrei] |
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| Themen: |
Children |
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| doi: |
10.34287/MMT.2(53).2022.3 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
DOAJ043952690 |
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| 245 | 1 | 0 | |a SERUM LEVEL OF SOME CYTOKINES IN CHILDREN 6-10 YEARS OLD WITH HIGH FREQUENCY OF ACUTE RESPIRATORY INFECTIONS |
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| 520 | |a Objective: improved diagnosis of immune disorders in children aged 6-10 years old, who are often ill od upper respiratory tract infections (URTI), on the basis of these data, further investigation of serum equalities of cytokines, a way of diagnosing with indications in healthy children. Materials and methods. There were 60 children of 6 to 10 years of age, from which 2 groups were formed: 1). children who are often ill with URTI (n=30); 2). children, who do not get sick often URTI (n=30). Results. among children of 6-10 years of age, as often ill with URTI, the frequency of registration of high indications in place of interleukin-6 blood serum (by 53.3%, p<0.05), TNF (by 63.3%, p <0.05) and low indications for interleukin-10 (by 33.3%, p<0.05), it was established that there was a high probability (odds ratio) of an increase serum interleukin-6, TNF and a decrease in interleukin-10 as a reference value, it is associated with the presence of an increased incidence of URTI in children. Conclusion. in children aged 6-10 years, as they often fall ill with URTI, may tend to intensify pro-inflammation of the immune reactions, which still does not ensure a decrease in serious illness on URTI and unsafe side of the development of opportunistic diseases. | ||
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