A Retrospective Analysis of Pain Etiology in Middle-Aged Patients with Peripheral Neuropathy

<i<Background and Objectives</i<: Correct assessment and a multidisciplinary approach appear to be extremely important in preventing peripheral neuropathy and its complications. The purpose of this study was to find the correlations and dissimilarities between different types of peripheral neuropathy, the occurrence of pain, and laboratory results. <i<Materials and Methods</i<: This retrospective study assessed 124 patients who were hospitalized in our neurology department due to various types of sensory or motor disturbances. The patients were eventually diagnosed with peripheral neuropathy, based on the electrophysiological study, anamnesis, physical examination, and laboratory results. The whole group was subjected to statistical analysis. <i<Results</i<: The mean age of patients was over 56 years, with a slight woman predominance. A statistically significant (<i<p</i< < 0.05) relationship between the place of residence and gender was seen, where more men than women live in the rural area, while more women than men live in the urban area. Most often we observed symmetric, sensorimotor, demyelinating, inflammatory, and chronic neuropathy. More than 40% of patients reported pain. A statistically significant correlation between the evolution/severity and the occurrence of pain was seen in subacute type (<i<p</i< < 0.05) and small fibre neuropathy (<i<p</i< < 0.01). <i<Conclusions</i<: A higher incidence of peripheral neuropathy in middle-aged people will become essential in the aging society with lifestyle and chronic disorders. Peripheral neuropathy is slightly more common in women than men and its occurrence may be influenced by work performed or internal and external factors. In the study group, more than 40% of patients reported pain, therefore the pain measurement for each patient should be implemented and repeated at every visit. An assessment of sodium level and, in women, markers of neuroinflammation level in the various types of peripheral neuropathy may be an interesting direction for the future..

Medienart:	E-Artikel

Erscheinungsjahr:	2021
Erschienen:	2021

Enthalten in:	Zur Gesamtaufnahme - volume:57
Enthalten in:	Medicina - 57(2021), 8, p 787

Sprache:	Englisch

Beteiligte Personen:	Anna K. Szewczyk [VerfasserIn] Anna Jamroz-Wiśniewska [VerfasserIn] Konrad Rejdak [VerfasserIn]

Links:	doi.org [kostenfrei] doaj.org [kostenfrei] www.mdpi.com [kostenfrei] Journal toc [kostenfrei] Journal toc [kostenfrei]

Themen:	Epidemiology Laboratory markers Medicine (General) Middle age Neuropathic pain Peripheral neuropathy Polyneuropathy

doi:	10.3390/medicina57080787

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	DOAJ034585281