Multiple sclerosis-related fatigue lacks a unified definition: A narrative review
Fatigue is the most common symptom in multiple sclerosis (MS). Although MS-related fatigue (MS-F) strongly affects quality of life and social performance of patients, there is currently a lack of knowledge about its pathophysiology, which in turns leads to poor objective diagnosis and management. Recent studies have attempted to explain potential etiologies as well as treatments for MS-F. However, it seems that without a consensus on its nature, these data could not provide a route to a successful approach. In this Article, we review definitions, epidemiology, risk factors and correlated comorbidities, pathophysiology, assessment methods, neuroimaging findings, and pharmacological and nonpharmacological treatments of MS-F. Further studies are warranted to define fatigue in MS patients more accurately, which could result in precise diagnosis and management..
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
|---|---|
| Enthalten in: |
Journal of Research in Medical Sciences - 27(2022), 1, Seite 24-24 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Iman Adibi [VerfasserIn] |
|---|
| Links: |
doi.org [kostenfrei] |
|---|
| Themen: |
Diagnosis |
|---|
| doi: |
10.4103/jrms.jrms_1401_20 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
DOAJ030352053 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | DOAJ030352053 | ||
| 003 | DE-627 | ||
| 005 | 20230307145633.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230226s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.4103/jrms.jrms_1401_20 |2 doi | |
| 035 | |a (DE-627)DOAJ030352053 | ||
| 035 | |a (DE-599)DOAJd36b9e9c221145d099f76eb03e1a680c | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 0 | |a Iman Adibi |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Multiple sclerosis-related fatigue lacks a unified definition: A narrative review |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Fatigue is the most common symptom in multiple sclerosis (MS). Although MS-related fatigue (MS-F) strongly affects quality of life and social performance of patients, there is currently a lack of knowledge about its pathophysiology, which in turns leads to poor objective diagnosis and management. Recent studies have attempted to explain potential etiologies as well as treatments for MS-F. However, it seems that without a consensus on its nature, these data could not provide a route to a successful approach. In this Article, we review definitions, epidemiology, risk factors and correlated comorbidities, pathophysiology, assessment methods, neuroimaging findings, and pharmacological and nonpharmacological treatments of MS-F. Further studies are warranted to define fatigue in MS patients more accurately, which could result in precise diagnosis and management. | ||
| 650 | 4 | |a diagnosis | |
| 650 | 4 | |a epidemiology | |
| 650 | 4 | |a etiology | |
| 650 | 4 | |a fatigue | |
| 650 | 4 | |a multiple sclerosis | |
| 650 | 4 | |a neuroimaging | |
| 650 | 4 | |a physiopathology | |
| 650 | 4 | |a risk factors | |
| 650 | 4 | |a therapy | |
| 653 | 0 | |a Medicine | |
| 653 | 0 | |a R | |
| 700 | 0 | |a Mehdi Sanayei |e verfasserin |4 aut | |
| 700 | 0 | |a Farinaz Tabibian |e verfasserin |4 aut | |
| 700 | 0 | |a Neda Ramezani |e verfasserin |4 aut | |
| 700 | 0 | |a Ahmad Pourmohammadi |e verfasserin |4 aut | |
| 700 | 0 | |a Kiarash Azimzadeh |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i In |t Journal of Research in Medical Sciences |d Wolters Kluwer Medknow Publications, 2005 |g 27(2022), 1, Seite 24-24 |w (DE-627)DOAJ000076686 |x 17357136 |7 nnns |
| 773 | 1 | 8 | |g volume:27 |g year:2022 |g number:1 |g pages:24-24 |
| 856 | 4 | 0 | |u https://doi.org/10.4103/jrms.jrms_1401_20 |z kostenfrei |
| 856 | 4 | 0 | |u https://doaj.org/article/d36b9e9c221145d099f76eb03e1a680c |z kostenfrei |
| 856 | 4 | 0 | |u http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2022;volume=27;issue=1;spage=24;epage=24;aulast=Adibi |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/1735-1995 |y Journal toc |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/1735-7136 |y Journal toc |z kostenfrei |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_DOAJ | ||
| 951 | |a AR | ||
| 952 | |d 27 |j 2022 |e 1 |h 24-24 | ||