The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy
Xerostomia is a common complication post-radiotherapy in patients with oral cancer. The acute and long-term side effects can considerably reduce the patient’s quality of life. The aim of our study was to perform analysis of salivary flow and pH in patients after radiotherapy. Methodology: Clinical and laboratory evaluations were conducted in the 2014–2019 period; out of a total 58 subjects aged between 45 and 84, 28 individuals with oral cancer were selected from St. Spiridon Hospital, Clinic of Maxillo-facial Surgery and Oncology Hospital, Iasi post-radiotherapy. Results: Significant downsized mean values of the hydrogen ion concentration (pH) in saliva (<i<p</i< < 0.001) were recorded in patients after radiotherapy, pH value = 4.580 (±1.051). The mean value of resting salivary flow (MRSF) was significantly lower for the group of patients with radiotherapy (MRSF) = 0.145 mL/min. In 89.29% of cases (25 post-radiotherapy cases), in order to perform oral complex rehabilitation treatment, several endodontic and periodontal treatments were performed. A total of 78.57% of the cases received complex oral rehabilitation as mobile or hybrid prostheses or fixed solutions. Conclusion: Understanding post-radiotherapy salivary biochemic modifications in patients with oral cancer could be of critical importance, in view of related oral disorder prevention..
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
|---|---|
| Enthalten in: |
Applied Sciences - 12(2022), 8, p 3708 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Bogdan Petru Bulancea [VerfasserIn] |
|---|
| Links: |
doi.org [kostenfrei] |
|---|
| doi: |
10.3390/app12083708 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
DOAJ029903408 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | DOAJ029903408 | ||
| 003 | DE-627 | ||
| 005 | 20240414115623.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230226s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3390/app12083708 |2 doi | |
| 035 | |a (DE-627)DOAJ029903408 | ||
| 035 | |a (DE-599)DOAJ2be47e95fbb84633b86b6f00a00c4163 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 050 | 0 | |a TA1-2040 | |
| 050 | 0 | |a QH301-705.5 | |
| 050 | 0 | |a QC1-999 | |
| 050 | 0 | |a QD1-999 | |
| 100 | 0 | |a Bogdan Petru Bulancea |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Xerostomia is a common complication post-radiotherapy in patients with oral cancer. The acute and long-term side effects can considerably reduce the patient’s quality of life. The aim of our study was to perform analysis of salivary flow and pH in patients after radiotherapy. Methodology: Clinical and laboratory evaluations were conducted in the 2014–2019 period; out of a total 58 subjects aged between 45 and 84, 28 individuals with oral cancer were selected from St. Spiridon Hospital, Clinic of Maxillo-facial Surgery and Oncology Hospital, Iasi post-radiotherapy. Results: Significant downsized mean values of the hydrogen ion concentration (pH) in saliva (<i<p</i< < 0.001) were recorded in patients after radiotherapy, pH value = 4.580 (±1.051). The mean value of resting salivary flow (MRSF) was significantly lower for the group of patients with radiotherapy (MRSF) = 0.145 mL/min. In 89.29% of cases (25 post-radiotherapy cases), in order to perform oral complex rehabilitation treatment, several endodontic and periodontal treatments were performed. A total of 78.57% of the cases received complex oral rehabilitation as mobile or hybrid prostheses or fixed solutions. Conclusion: Understanding post-radiotherapy salivary biochemic modifications in patients with oral cancer could be of critical importance, in view of related oral disorder prevention. | ||
| 650 | 4 | |a oral cancer | |
| 650 | 4 | |a post-radiotherapy (RT) | |
| 650 | 4 | |a salivary pH | |
| 650 | 4 | |a salivary flow rate (SFR) | |
| 650 | 4 | |a intraoral complex rehabilitation treatment | |
| 650 | 4 | |a stomatognatic system (SS) | |
| 653 | 0 | |a Technology | |
| 653 | 0 | |a T | |
| 653 | 0 | |a Engineering (General). Civil engineering (General) | |
| 653 | 0 | |a Biology (General) | |
| 653 | 0 | |a Physics | |
| 653 | 0 | |a Chemistry | |
| 700 | 0 | |a Laura Elisabeta Checherita |e verfasserin |4 aut | |
| 700 | 0 | |a Georgeta Liliana Foia |e verfasserin |4 aut | |
| 700 | 0 | |a Ovidiu Stamatin |e verfasserin |4 aut | |
| 700 | 0 | |a Silvia Teslaru |e verfasserin |4 aut | |
| 700 | 0 | |a Iulian Costin Lupu |e verfasserin |4 aut | |
| 700 | 0 | |a Delia Gabriela Ciobanu |e verfasserin |4 aut | |
| 700 | 0 | |a Eduard-Radu Cernei |e verfasserin |4 aut | |
| 700 | 0 | |a Grierosu Carmen |e verfasserin |4 aut | |
| 700 | 0 | |a Mariana Postolache |e verfasserin |4 aut | |
| 700 | 0 | |a Eliza Maria Froicu |e verfasserin |4 aut | |
| 700 | 0 | |a Liliana Gabriela Halitchi |e verfasserin |4 aut | |
| 700 | 0 | |a Liana Aminov |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i In |t Applied Sciences |d MDPI AG, 2012 |g 12(2022), 8, p 3708 |w (DE-627)DOAJ000144045 |x 20763417 |7 nnns |
| 773 | 1 | 8 | |g volume:12 |g year:2022 |g number:8, p 3708 |
| 856 | 4 | 0 | |u https://doi.org/10.3390/app12083708 |z kostenfrei |
| 856 | 4 | 0 | |u https://doaj.org/article/2be47e95fbb84633b86b6f00a00c4163 |z kostenfrei |
| 856 | 4 | 0 | |u https://www.mdpi.com/2076-3417/12/8/3708 |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/2076-3417 |y Journal toc |z kostenfrei |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_DOAJ | ||
| 951 | |a AR | ||
| 952 | |d 12 |j 2022 |e 8, p 3708 | ||