HGV prevalence in patients with Type II diabetes mellitus and HGV infection
Background: In this study, because of genomic mimicry of viruses and resemblance in transmission route of HCV and GBV-C/HGV infection, we aimed to investigate possible relationships between chronic GBV-C/HGV infection and NIDDM in 88 patients with type-2 diabetes and 89 gender- and age-matched non-diabetic controls.Methodology: We used polymerase chain reaction (PCR) methods and immunoassay systems for determining viral genome and antibody, respectively to investigate epidemiology of HGV/GBV-C virus in diabetic patients. Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were measured and compared between patient and control groups.Results: Rates of GBV-C/HGV RNA; and anti-GBV-C/HGV antibody were 2.3% and 2.3%; and 0% and 2.4%, in patients and controls, respectively (GBV-C/HGV, p=0.158; anti-HGV p=0.825). HBsAg, HBV and Anti HCV positivity rates in diabetic patients and controls were 3.4%, 36.8%, 1.1%, respectively; in non-diabetic controls 2.2%, 32.6%, 0%, respectively (for HBs Ag, p= 0.657,for HBV p= 0.427 and for Anti HCV p= 0.321).Conclusions: Differences were not found in the rates of HCV, HBV and GBV-C/HGV positivity between patients with type 2 diabetes and control groups. Expanded studies may be necessary to form more conclusive interpretations..
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2007 |
---|---|
Erschienen: |
2007 |
Enthalten in: |
Zur Gesamtaufnahme - volume:1 |
---|---|
Enthalten in: |
Journal of Infection in Developing Countries - 1(2007), 2, Seite 189-194 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Dilek Kilic,1 Sedat Kaygusuz,1 Canan Agalar,1 Sefa Guliter,2 Aytul Cakmak,3 and Mesut Sezikli2 [VerfasserIn] |
---|
Links: |
doaj.org [kostenfrei] |
---|
Themen: |
Diabetes mellitus. |
---|
Förderinstitution / Projekttitel: |
|
---|
PPN (Katalog-ID): |
DOAJ026532174 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | DOAJ026532174 | ||
003 | DE-627 | ||
005 | 20230307102314.0 | ||
007 | cr uuu---uuuuu | ||
008 | 230226s2007 xx |||||o 00| ||eng c | ||
035 | |a (DE-627)DOAJ026532174 | ||
035 | |a (DE-599)DOAJ23ef33e6800941349043b09acdbf82b4 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
050 | 0 | |a RC31-1245 | |
050 | 0 | |a QR1-502 | |
100 | 0 | |a Dilek Kilic,1 Sedat Kaygusuz,1 Canan Agalar,1 Sefa Guliter,2 Aytul Cakmak,3 and Mesut Sezikli2 |e verfasserin |4 aut | |
245 | 1 | 0 | |a HGV prevalence in patients with Type II diabetes mellitus and HGV infection |
264 | 1 | |c 2007 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
520 | |a Background: In this study, because of genomic mimicry of viruses and resemblance in transmission route of HCV and GBV-C/HGV infection, we aimed to investigate possible relationships between chronic GBV-C/HGV infection and NIDDM in 88 patients with type-2 diabetes and 89 gender- and age-matched non-diabetic controls.Methodology: We used polymerase chain reaction (PCR) methods and immunoassay systems for determining viral genome and antibody, respectively to investigate epidemiology of HGV/GBV-C virus in diabetic patients. Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were measured and compared between patient and control groups.Results: Rates of GBV-C/HGV RNA; and anti-GBV-C/HGV antibody were 2.3% and 2.3%; and 0% and 2.4%, in patients and controls, respectively (GBV-C/HGV, p=0.158; anti-HGV p=0.825). HBsAg, HBV and Anti HCV positivity rates in diabetic patients and controls were 3.4%, 36.8%, 1.1%, respectively; in non-diabetic controls 2.2%, 32.6%, 0%, respectively (for HBs Ag, p= 0.657,for HBV p= 0.427 and for Anti HCV p= 0.321).Conclusions: Differences were not found in the rates of HCV, HBV and GBV-C/HGV positivity between patients with type 2 diabetes and control groups. Expanded studies may be necessary to form more conclusive interpretations. | ||
650 | 4 | |a hepatitis | |
650 | 4 | |a GBV-C/HGV | |
650 | 4 | |a diabetes mellitus. | |
653 | 0 | |a Internal medicine | |
653 | 0 | |a Microbiology | |
773 | 0 | 8 | |i In |t Journal of Infection in Developing Countries |d The Journal of Infection in Developing Countries, 2019 |g 1(2007), 2, Seite 189-194 |w (DE-627)DOAJ000120642 |x 19722680 |7 nnns |
773 | 1 | 8 | |g volume:1 |g year:2007 |g number:2 |g pages:189-194 |
856 | 4 | 0 | |u https://doaj.org/article/23ef33e6800941349043b09acdbf82b4 |z kostenfrei |
856 | 4 | 0 | |u http://www.oloep.org/jidc/content.asp?id=1060 |z kostenfrei |
856 | 4 | 2 | |u https://doaj.org/toc/1972-2680 |y Journal toc |z kostenfrei |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_DOAJ | ||
951 | |a AR | ||
952 | |d 1 |j 2007 |e 2 |h 189-194 |