Clinical characteristics of Chilean patients with rheumatic diseases and COVID-19: data from the Covid-19 Global Rheumatology Alliance physician-reported registry
Objective: The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), has registered more than 234 million confirmed cases and more than 4.7 million deaths throughout the world until October 2, 2021. During the last few months, a significant number of reports of COVID-19 in patients with rheumatic diseases have been published. In this study the objective is to report the clinical characteristics of Chilean patients with rheumatic diseases and COVID-19 reported in the “Global Rheumatology Alliance” (GRA) physician registration platform. Materials and Methods: Chilean patients with rheumatic diseases and COVID-19 were included in the Covid-19 GRA physician-reported registry. Results: 54 patients were included. The most common primary rheumatic disease was rheumatoid arthritis (RA) with 28 cases (51.9%). 30 patients (55.6%) used corticosteroids, of which 20 (66.7%) used a dose of 10 mg or less. 33 patients (61.1%) only used conventional DMARDs, 4 (7.4%) only biological, and 6 (11.1%) the combination. A total of 35 patients (64.8%) had to be hospitalized. 2 patients (3.7%) died. 26 patients of the 35 hospitalized (74.2%) required some type of ventilatory support, of which 5 (19.2%) required non-invasive and 8 (30.8%) invasive mechanical ventilation or extracorporeal membrane oxygenation (ECMO). Discussion: Most of included Chilean rheumatic patients were hospitalized, with a low mortality rate but with a high percentage of patients requiring at least non-invasive mechanical ventilation..
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:4 |
|---|---|
| Enthalten in: |
Global Rheumatology - 4(2022) |
| Sprache: |
Englisch ; Spanisch ; Portugiesisch |
|---|
| Beteiligte Personen: |
Oriela Martínez Hernández [VerfasserIn] |
|---|
| Links: |
doi.org [kostenfrei] |
|---|
| Themen: |
Brief report |
|---|
| doi: |
10.46856/grp.12.e113 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
DOAJ02400166X |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | DOAJ02400166X | ||
| 003 | DE-627 | ||
| 005 | 20230307072001.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230226s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.46856/grp.12.e113 |2 doi | |
| 035 | |a (DE-627)DOAJ02400166X | ||
| 035 | |a (DE-599)DOAJ060448d918f845a1b6eabd2e06a7d3ff | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng |a spa |a por | ||
| 050 | 0 | |a R5-920 | |
| 050 | 0 | |a RC925-935 | |
| 100 | 0 | |a Oriela Martínez Hernández |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Clinical characteristics of Chilean patients with rheumatic diseases and COVID-19: data from the Covid-19 Global Rheumatology Alliance physician-reported registry |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Objective: The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), has registered more than 234 million confirmed cases and more than 4.7 million deaths throughout the world until October 2, 2021. During the last few months, a significant number of reports of COVID-19 in patients with rheumatic diseases have been published. In this study the objective is to report the clinical characteristics of Chilean patients with rheumatic diseases and COVID-19 reported in the “Global Rheumatology Alliance” (GRA) physician registration platform. Materials and Methods: Chilean patients with rheumatic diseases and COVID-19 were included in the Covid-19 GRA physician-reported registry. Results: 54 patients were included. The most common primary rheumatic disease was rheumatoid arthritis (RA) with 28 cases (51.9%). 30 patients (55.6%) used corticosteroids, of which 20 (66.7%) used a dose of 10 mg or less. 33 patients (61.1%) only used conventional DMARDs, 4 (7.4%) only biological, and 6 (11.1%) the combination. A total of 35 patients (64.8%) had to be hospitalized. 2 patients (3.7%) died. 26 patients of the 35 hospitalized (74.2%) required some type of ventilatory support, of which 5 (19.2%) required non-invasive and 8 (30.8%) invasive mechanical ventilation or extracorporeal membrane oxygenation (ECMO). Discussion: Most of included Chilean rheumatic patients were hospitalized, with a low mortality rate but with a high percentage of patients requiring at least non-invasive mechanical ventilation. | ||
| 650 | 4 | |a rheumatic disease | |
| 650 | 4 | |a pandemic | |
| 650 | 4 | |a covid-19 | |
| 650 | 4 | |a brief report | |
| 653 | 0 | |a Medicine (General) | |
| 653 | 0 | |a Diseases of the musculoskeletal system | |
| 700 | 0 | |a Francisca Valenzuela |e verfasserin |4 aut | |
| 700 | 0 | |a Sebastian Ibañez |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i In |t Global Rheumatology |d Panamerican League of Associations of Rheumatology (PANLAR), 2022 |g 4(2022) |w (DE-627)DOAJ078605350 |x 27095533 |7 nnns |
| 773 | 1 | 8 | |g volume:4 |g year:2022 |
| 856 | 4 | 0 | |u https://doi.org/10.46856/grp.12.e113 |z kostenfrei |
| 856 | 4 | 0 | |u https://doaj.org/article/060448d918f845a1b6eabd2e06a7d3ff |z kostenfrei |
| 856 | 4 | 0 | |u https://www.globalrheumpanlar.org/manuscrito-comentarios-y-respuestas/brief-report-caracteristicas-clinicas-de-pacientes-chilenos-con?language=en |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/2709-5533 |y Journal toc |z kostenfrei |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_DOAJ | ||
| 951 | |a AR | ||
| 952 | |d 4 |j 2022 | ||