Comparison of troponin levels in isolated middle cerebral artery and anterior system tandem occlusion treated with mechanical thrombectomy

INTRODUCTION: Ischemic stroke is the most common disability worldwide and the second most common cause of mortality. One of the major causes of mortality in patients with ischemic stroke is cardiac complications. However, high levels of troponin may be caused in patients with ischemic stroke and many of the systemic diseases that has a risk for the stroke. In this study, we aimed to investigate troponin levels of stroke patients who were treated with mechanical thrombectomy and the resulting risk factors for stroke, mortality and physical dependence at the end of the third month in tandem and M1 occlusions. METHODS: In this study, troponin values are examined retrospectively in stroke patients with tandem occlusion of the anterior circulation and middle cerebral artery M1 occlusions, who were treated between January 2015 and February 2019. SPSS Windows 23 package program was used in the statistical analysis of the data obtained from the study. Troponin values in tandem and middle cerebral artery occlusion were compared with chi-square method. Results were evaluated at 95% confidence interval and p<0.05 level of significance. RESULTS: When the mortality rates between tandem and MCA occlusions were examined at the end of the third month, mortality rates were higher in tandem occlusions and there was a statistically significant difference between the two groups (p: 0.027). There was no significant difference between tandem and MCA occlusions in terms of troponin values (p: 0.63). Patients with troponin values above 0.028 ng / mL had significantly higher mortality at 3 months. DISCUSSION AND CONCLUSION: There is a relationship between mortality and elevation of troponin levels in patients who had tandem and MCA occlusions. However, there was no difference between tandem and MCA occlusions in terms of troponin values significantly. There is a need to further study the impact of ischemic stroke on troponin levels with randomized, controlled studies..

Medienart:	E-Artikel

Erscheinungsjahr:	2019
Erschienen:	2019

Enthalten in:	Zur Gesamtaufnahme - volume:25
Enthalten in:	Türk Beyin Damar Hastalıkları Dergisi - 25(2019), 2, Seite 113-117

Sprache:	Englisch ; Türkisch

Beteiligte Personen:	Nihat Şengeze [VerfasserIn] Semih Giray [VerfasserIn] Yusuf İnanç [VerfasserIn] Alper Eren [VerfasserIn] Sedat Yaşin [VerfasserIn]

Links:	doi.org [kostenfrei] doaj.org [kostenfrei] www.journalagent.com [kostenfrei] Journal toc [kostenfrei] Journal toc [kostenfrei]

Themen:	Endovascular treatment Ischemic stroke Mechanical thrombectomy Medicine Middle cerebral artery occlusion R Tandem occlusion Troponin level

doi:	10.5505/tbdhd.2019.53824

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	DOAJ017427614