The Influence of Atrial Fibrillation on In-Hospital Mortality in People with Hospital-Acquired Pneumonia: An Observational, Sex-Stratified Study
(1) Background: The study aimed to analyze the influence of atrial fibrillation (AF) prior to hospital admission (“prevalent”) and new-onset AF diagnosed during hospital admission (“incident”) on in-hospital mortality (IHM) in women and men who developed hospital-acquired pneumonia (HAP) in Spain (2016–2019). (2) Methods: We used the Spanish Register of Specialized Care-Basic Minimum Database. (3) Results: We analyzed 38,814 cases of HAP (34.6% women; 13.5% ventilator-associated). Prevalent AF was coded in 19.9% (<i<n</i< = 7742), and incident AF in 5.5% (<i<n</i< = 2136) of HAP. Crude IHM was significantly higher for prevalent AF (34.22% vs. 27.35%, <i<p</i< < 0.001) and for incident AF (35.81% vs. 28.31%, <i<p</i< < 0.001) compared to no AF. After propensity score matching, IHM among women and men with prevalent AF was higher than among women and men with no AF (among women, 32.89% vs. 30.11%, <i<p</i< = 0.021; among men, 35.05% vs. 32.46%, <i<p</i< = 0.008). Similarly, IHM among women and men with incident AF was higher than among women and men with no AF (among women, 36.23% vs. 29.90%, <i<p</i< = 0.013; among men, 35.62% vs. 30.47%; <i<p</i< = 0.003). Sex was associated with a higher IHM only in people with incident AF (for female, OR = 1.21; 95% CI: 1.01–1.57). (4) Conclusions: Both prevalent and incident AF were associated with higher IHM in people who developed HAP. Female sex was associated with a higher IHM in incident AF..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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| Enthalten in: |
Journal of Clinical Medicine - 11(2022), 5, p 1179 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Jose M. de Miguel-Yanes [VerfasserIn] |
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| Links: |
doi.org [kostenfrei] |
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| Themen: |
Atrial fibrillation |
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| doi: |
10.3390/jcm11051179 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
DOAJ016180534 |
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| 520 | |a (1) Background: The study aimed to analyze the influence of atrial fibrillation (AF) prior to hospital admission (“prevalent”) and new-onset AF diagnosed during hospital admission (“incident”) on in-hospital mortality (IHM) in women and men who developed hospital-acquired pneumonia (HAP) in Spain (2016–2019). (2) Methods: We used the Spanish Register of Specialized Care-Basic Minimum Database. (3) Results: We analyzed 38,814 cases of HAP (34.6% women; 13.5% ventilator-associated). Prevalent AF was coded in 19.9% (<i<n</i< = 7742), and incident AF in 5.5% (<i<n</i< = 2136) of HAP. Crude IHM was significantly higher for prevalent AF (34.22% vs. 27.35%, <i<p</i< < 0.001) and for incident AF (35.81% vs. 28.31%, <i<p</i< < 0.001) compared to no AF. After propensity score matching, IHM among women and men with prevalent AF was higher than among women and men with no AF (among women, 32.89% vs. 30.11%, <i<p</i< = 0.021; among men, 35.05% vs. 32.46%, <i<p</i< = 0.008). Similarly, IHM among women and men with incident AF was higher than among women and men with no AF (among women, 36.23% vs. 29.90%, <i<p</i< = 0.013; among men, 35.62% vs. 30.47%; <i<p</i< = 0.003). Sex was associated with a higher IHM only in people with incident AF (for female, OR = 1.21; 95% CI: 1.01–1.57). (4) Conclusions: Both prevalent and incident AF were associated with higher IHM in people who developed HAP. Female sex was associated with a higher IHM in incident AF. | ||
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| 700 | 0 | |a Ana Lopez-de-Andres |e verfasserin |4 aut | |
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