Evaluation of 17 Cases of Adult Tuberculous Meningitis
Adult tuberculous meningitis is an extra-pulmonary form of tuberculosis which, because of a rapid course and neurological sequela, leads to high morbidity and mortality. For this reason, an early diagnosis is important but is not always possible. The aim of this study, which was carried out between 1991-1995, was to evaluate the factors affecting the prognosis of diseases in patients which had been diagnosied as tuberculous meningitis using the patients history, clinical picture, and laboratory and radiological findings. Fifty nine percent of the patients were between 25-45 years of age. The rate of mortality in these patients 47% and when they were admitted to the hospital, 62.5% were in the second stage of the disease. In 15 (88.2%) of all patients, the symptoms had occurred 2 weeks or more before hospitalization. In the microscobic examination of CSF of 5 (29.4%) of the patients, acid fast bacilli were seen. However, M. tuberculosis grew in the cultures of CSF of only 2 of these. Evidence of active or previous pulmonary tuberculosis was found in 4 (23.5%) of our patients. Ventriculoperitoneal shuts were placed in 3 out of 8 patients who developed hydrocephalus. Multipl tüberculomas which decreased with antituberculous treatment were detected in 2 patients during treatment. In conclusion, in patients with tuberculous meningitis, the most important factors affecting the prognosis is the time between the development of symptoms and treatment as well as the neurologic phase..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
1997 |
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| Erschienen: |
1997 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:2 |
|---|---|
| Enthalten in: |
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi - 2(1997), 1, Seite 55-60 |
| Sprache: |
Englisch ; Türkisch |
|---|
| Beteiligte Personen: |
Yeşim TAŞOVA [VerfasserIn] |
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| Links: |
doaj.org [kostenfrei] |
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| Themen: |
Adult |
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| Förderinstitution / Projekttitel: |
|
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| PPN (Katalog-ID): |
DOAJ012705551 |
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| 520 | |a Adult tuberculous meningitis is an extra-pulmonary form of tuberculosis which, because of a rapid course and neurological sequela, leads to high morbidity and mortality. For this reason, an early diagnosis is important but is not always possible. The aim of this study, which was carried out between 1991-1995, was to evaluate the factors affecting the prognosis of diseases in patients which had been diagnosied as tuberculous meningitis using the patients history, clinical picture, and laboratory and radiological findings. Fifty nine percent of the patients were between 25-45 years of age. The rate of mortality in these patients 47% and when they were admitted to the hospital, 62.5% were in the second stage of the disease. In 15 (88.2%) of all patients, the symptoms had occurred 2 weeks or more before hospitalization. In the microscobic examination of CSF of 5 (29.4%) of the patients, acid fast bacilli were seen. However, M. tuberculosis grew in the cultures of CSF of only 2 of these. Evidence of active or previous pulmonary tuberculosis was found in 4 (23.5%) of our patients. Ventriculoperitoneal shuts were placed in 3 out of 8 patients who developed hydrocephalus. Multipl tüberculomas which decreased with antituberculous treatment were detected in 2 patients during treatment. In conclusion, in patients with tuberculous meningitis, the most important factors affecting the prognosis is the time between the development of symptoms and treatment as well as the neurologic phase. | ||
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