Trends in multidrug-resistant tuberculosis in Tehran, Iran: an analysis of published data
Introduction: Multidrug-resistant tuberculosis (MDR-TB) is one of the major public health threats especially in developing countries. In Iran, the emergence and spread of MDR-TB are likely to pose a significant problem for the National Tubeculosis Control Program (NTP). In this study, to determine the trend of MDR-TB in Tehran, the results of published studies were analyzed.Methods: Several databases were searched, including Medline, Embase, Web of Science and Iranian databases. Studies which report the preva of MDR-TB by World Health Organization (WHO)-endorsed drug susceptibility testing (DST) methods were included in the study. Data were analyzed with SPSS 20 (SPSS, Chicago, Illinois, USA).Results: Analysis of the MDR-TB trend did not show any increase among new TB cases, but the trend of MDR-TB was significantly increased among previously treated cases. The prevalence of MDR-TB from 48.0% in 1996 reached 58.0% in 2004 (P<0.05). Conclusions: Our analysis shows an increasing trend in MDR-TB, parlarly in retreatment cases. This study strongly highlights the need to develop further strategies for surveillance, monitoring, and management of MDR-TB cases..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:14, p Doc11 |
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| Enthalten in: |
GMS Hygiene and Infection Control - 14, p Doc11(2019) |
| Sprache: |
Deutsch ; Englisch |
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| Beteiligte Personen: |
Nasiri, Mohammad Javad [VerfasserIn] |
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| Links: |
doi.org [kostenfrei] |
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| Themen: |
Iran |
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| doi: |
10.3205/dgkh000327 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
DOAJ009120289 |
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| 520 | |a Introduction: Multidrug-resistant tuberculosis (MDR-TB) is one of the major public health threats especially in developing countries. In Iran, the emergence and spread of MDR-TB are likely to pose a significant problem for the National Tubeculosis Control Program (NTP). In this study, to determine the trend of MDR-TB in Tehran, the results of published studies were analyzed.Methods: Several databases were searched, including Medline, Embase, Web of Science and Iranian databases. Studies which report the preva of MDR-TB by World Health Organization (WHO)-endorsed drug susceptibility testing (DST) methods were included in the study. Data were analyzed with SPSS 20 (SPSS, Chicago, Illinois, USA).Results: Analysis of the MDR-TB trend did not show any increase among new TB cases, but the trend of MDR-TB was significantly increased among previously treated cases. The prevalence of MDR-TB from 48.0% in 1996 reached 58.0% in 2004 (P<0.05). Conclusions: Our analysis shows an increasing trend in MDR-TB, parlarly in retreatment cases. This study strongly highlights the need to develop further strategies for surveillance, monitoring, and management of MDR-TB cases. | ||
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