Clinical effects of elective neck dissection on 5-year survival rate of patients with early oral squamous cell carcinoma
Objective To investigate the effect of elective neck dissection on the 5-year survival rate of patients with early oral squamous cell carcinoma. Methods The data of 100 patients with early oral squamous cell carcinoma (cT1-2N0M0) were retrospectively analyzed. In 61 cases, the primary tumor was subjected to elective neck dissection (END). Neck observation and follow-up (NOF) were performed in 39 cases with enlarged resection of primary lesions. Clinicopathological data such as pT staging, pathology classification,the rate of cervical lymph node metastasis and the 5-year survival rate of the patients were statistically analyzed. Results The 5-year survival rates of the END and NOF groups were 86.9% and 69.2%, respectively, and the difference was statistically significant (P=0.028). END treatment was significantly better than NOF in controlling cervical lymph node metastasis in early oral squamous cell carcinoma (P=0.009). After stratified analysis of histopathological features, the 5-year survival rate of patients with pathological T2 (pT2) stage OSCC in the END group was significantly higher than that in the NOF group (P=0.020). The 5-year survival rate of patients with moderate and poorly differentiated pathological grade OSCC in the END group was significantly higher than that in the NOF group (P=0.013). Conclusion END is effective for the management of the cervical lymph node metastasis rate in early OSCC patients. For patients with pT2 stage or low differentiation pathological grade, active END can significantly improve the 5-year survival rate..
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2022 |
---|---|
Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
---|---|
Enthalten in: |
口腔疾病防治 - 30(2022), 4, Seite 266-271 |
Sprache: |
Chinesisch |
---|
Beteiligte Personen: |
GE Shaowen [VerfasserIn] |
---|
Links: |
doi.org [kostenfrei] |
---|
Themen: |
Cervical lymph node metastasis, |
---|
doi: |
10.12016/j.issn.2096-1456.2022.04.006 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
DOAJ008065659 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | DOAJ008065659 | ||
003 | DE-627 | ||
005 | 20230310003404.0 | ||
007 | cr uuu---uuuuu | ||
008 | 230225s2022 xx |||||o 00| ||chi c | ||
024 | 7 | |a 10.12016/j.issn.2096-1456.2022.04.006 |2 doi | |
035 | |a (DE-627)DOAJ008065659 | ||
035 | |a (DE-599)DOAJf58a413ea5984a1c85411ba1b0aac08a | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a chi | ||
100 | 0 | |a GE Shaowen |e verfasserin |4 aut | |
245 | 1 | 0 | |a Clinical effects of elective neck dissection on 5-year survival rate of patients with early oral squamous cell carcinoma |
264 | 1 | |c 2022 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
520 | |a Objective To investigate the effect of elective neck dissection on the 5-year survival rate of patients with early oral squamous cell carcinoma. Methods The data of 100 patients with early oral squamous cell carcinoma (cT1-2N0M0) were retrospectively analyzed. In 61 cases, the primary tumor was subjected to elective neck dissection (END). Neck observation and follow-up (NOF) were performed in 39 cases with enlarged resection of primary lesions. Clinicopathological data such as pT staging, pathology classification,the rate of cervical lymph node metastasis and the 5-year survival rate of the patients were statistically analyzed. Results The 5-year survival rates of the END and NOF groups were 86.9% and 69.2%, respectively, and the difference was statistically significant (P=0.028). END treatment was significantly better than NOF in controlling cervical lymph node metastasis in early oral squamous cell carcinoma (P=0.009). After stratified analysis of histopathological features, the 5-year survival rate of patients with pathological T2 (pT2) stage OSCC in the END group was significantly higher than that in the NOF group (P=0.020). The 5-year survival rate of patients with moderate and poorly differentiated pathological grade OSCC in the END group was significantly higher than that in the NOF group (P=0.013). Conclusion END is effective for the management of the cervical lymph node metastasis rate in early OSCC patients. For patients with pT2 stage or low differentiation pathological grade, active END can significantly improve the 5-year survival rate. | ||
650 | 4 | |a oral cancer, | |
650 | 4 | |a squamous cell carcinoma, | |
650 | 4 | |a early stage, | |
650 | 4 | |a poorly differentiation, | |
650 | 4 | |a elective neck dissection, | |
650 | 4 | |a cervical lymph node metastasis, | |
650 | 4 | |a occult metastasis, | |
650 | 4 | |a depth of invasion, | |
650 | 4 | |a survival rate, | |
653 | 0 | |a Medicine | |
653 | 0 | |a R | |
700 | 0 | |a LIAO Shengkai |e verfasserin |4 aut | |
700 | 0 | |a ZHAN Zhaojun |e verfasserin |4 aut | |
700 | 0 | |a LI Xiaoliang |e verfasserin |4 aut | |
700 | 0 | |a GENG Linya |e verfasserin |4 aut | |
700 | 0 | |a ZHOU Qi |e verfasserin |4 aut | |
773 | 0 | 8 | |i In |t 口腔疾病防治 |d Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases, 2019 |g 30(2022), 4, Seite 266-271 |w (DE-627)DOAJ000123072 |x 20961456 |7 nnns |
773 | 1 | 8 | |g volume:30 |g year:2022 |g number:4 |g pages:266-271 |
856 | 4 | 0 | |u https://doi.org/10.12016/j.issn.2096-1456.2022.04.006 |z kostenfrei |
856 | 4 | 0 | |u https://doaj.org/article/f58a413ea5984a1c85411ba1b0aac08a |z kostenfrei |
856 | 4 | 0 | |u http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2022.04.006 |z kostenfrei |
856 | 4 | 2 | |u https://doaj.org/toc/2096-1456 |y Journal toc |z kostenfrei |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_DOAJ | ||
951 | |a AR | ||
952 | |d 30 |j 2022 |e 4 |h 266-271 |