Sero-Prevalence of SARS-CoV-2 Antibodies in High-Risk Populations in Vietnam

As a response to the coronavirus disease 2019 (COVID-19) pandemic, Vietnam enforced strict quarantine, contact tracing and physical distancing policies resulting in one of the lowest numbers of individuals infected with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) globally. This study aimed to determine the prevalence of SARS-CoV-2 antibody positivity among high-risk populations in Vietnam. A prevalence survey was undertaken within four communities in Vietnam, where at least two COVID-19 cases had been confirmed. Participants were classified according to the location of exposure: household contacts, close contacts, community members, and healthcare workers (HCWs) responsible for treating COVID-19 cases. Participants completed a baseline questionnaire and SARS-CoV-2 IgG antibodies were quantified using a commercial assay. A total of 3049 community members and 149 health care workers consented to the study. Among 13 individuals who were seropositive (0.4%), five household contacts (5/27, 18.5%), one close contact (1/53, 1.9%), and seven community members (7/2954, 0.2%) had detectable SARS-CoV-2 antibodies. All HCWs were negative for SARS-CoV-2 antibodies. Participants were tested a median of 15.1 (interquartile range from 14.9 to 15.2) weeks after exposure. Our study found a low prevalence of SARS-CoV-2 antibodies in high-risk communities and healthcare workers in communities in Vietnam with known COVID-19 cases..

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:18

Enthalten in:

International Journal of Environmental Research and Public Health - 18(2021), 6353, p 6353

Sprache:

Englisch

Beteiligte Personen:

Tasnim Hasan [VerfasserIn]
Thach Ngoc Pham [VerfasserIn]
Thu Anh Nguyen [VerfasserIn]
Hien Thi Thu Le [VerfasserIn]
Duyet Van Le [VerfasserIn]
Thuy Thi Dang [VerfasserIn]
Trang Dinh Van [VerfasserIn]
Yen Ngoc Pham [VerfasserIn]
Ha Viet Nguyen [VerfasserIn]
Giang Linh Tran [VerfasserIn]
Van Thi Cam Nguyen [VerfasserIn]
Thanh Trung Nguyen [VerfasserIn]
Viet Quang Truong [VerfasserIn]
Than Huu Dao [VerfasserIn]
Chung Thanh Le [VerfasserIn]
Nam Tan Truong [VerfasserIn]
Hoang Trung Vo [VerfasserIn]
Phuc Thanh Le [VerfasserIn]
Thao Thanh Nguyen [VerfasserIn]
Vinh Van Luu [VerfasserIn]
Vinh Dai Nguyen [VerfasserIn]
Brett G. Toelle [VerfasserIn]
Guy B. Marks [VerfasserIn]
Greg J. Fox [VerfasserIn]

Links:

doi.org [kostenfrei]
doaj.org [kostenfrei]
www.mdpi.com [kostenfrei]
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Themen:

COVID-19
Medicine
R
SARS-CoV-2
Seroprevalence
Vietnam

doi:

10.3390/ijerph18126353

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

DOAJ003578259