Human respiratory viruses, including SARS-CoV-2, circulating in the winter season 2019–2020 in Parma, Northern Italy
Objectives: The aim of this study was to determine the prevalence of respiratory virus infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), during the winter period December 2019 to March 2020, via a tertiary care hospital-based survey in Parma, Northern Italy. Methods: A total of 906 biological samples from the respiratory tract were analysed by both conventional assays (including culture) and molecular assays targeting nucleic acids of SARS-CoV-2 and other respiratory viruses. Results: Overall, 474 samples (52.3%) were positive for at least one virus, with a total of 583 viruses detected. Single infections were detected in 380 (80.2%) samples and mixed infections were detected in 94 (19.8%). Respiratory syncytial virus (138/583, 23.7%) and rhinovirus (130/583, 22.3%) were the most commonly identified viruses, followed by SARS-CoV-2 (82/583, 14.1%). Respiratory syncytial virus predominated until February, with 129 detections; it then decreased drastically in March to only nine detections. SARS-CoV-2 was absent in the study area until February 26, 2020 and then reached 82 detections in just over a month. SARS-CoV-2 was found in mixed infections in only three cases, all observed in children younger than 1 year old. Conclusions: This study showed a completely different trend between SARS-CoV-2 and the ‘common’ respiratory viruses: the common viruses mostly affected children, without any distinction according to sex, while SARS-CoV-2 mostly affected adult males..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:102 |
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| Enthalten in: |
International Journal of Infectious Diseases - 102(2021), Seite 79-84 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Adriana Calderaro [VerfasserIn] |
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| Links: |
doi.org [kostenfrei] |
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| Themen: |
Diagnosis |
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| doi: |
10.1016/j.ijid.2020.09.1473 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
DOAJ001858548 |
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| 245 | 1 | 0 | |a Human respiratory viruses, including SARS-CoV-2, circulating in the winter season 2019–2020 in Parma, Northern Italy |
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| 520 | |a Objectives: The aim of this study was to determine the prevalence of respiratory virus infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), during the winter period December 2019 to March 2020, via a tertiary care hospital-based survey in Parma, Northern Italy. Methods: A total of 906 biological samples from the respiratory tract were analysed by both conventional assays (including culture) and molecular assays targeting nucleic acids of SARS-CoV-2 and other respiratory viruses. Results: Overall, 474 samples (52.3%) were positive for at least one virus, with a total of 583 viruses detected. Single infections were detected in 380 (80.2%) samples and mixed infections were detected in 94 (19.8%). Respiratory syncytial virus (138/583, 23.7%) and rhinovirus (130/583, 22.3%) were the most commonly identified viruses, followed by SARS-CoV-2 (82/583, 14.1%). Respiratory syncytial virus predominated until February, with 129 detections; it then decreased drastically in March to only nine detections. SARS-CoV-2 was absent in the study area until February 26, 2020 and then reached 82 detections in just over a month. SARS-CoV-2 was found in mixed infections in only three cases, all observed in children younger than 1 year old. Conclusions: This study showed a completely different trend between SARS-CoV-2 and the ‘common’ respiratory viruses: the common viruses mostly affected children, without any distinction according to sex, while SARS-CoV-2 mostly affected adult males. | ||
| 650 | 4 | |a Respiratory viruses | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a Diagnosis | |
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| 650 | 4 | |a Pandemic | |
| 650 | 4 | |a Molecular assays | |
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| 700 | 0 | |a Flora De Conto |e verfasserin |4 aut | |
| 700 | 0 | |a Mirko Buttrini |e verfasserin |4 aut | |
| 700 | 0 | |a Giovanna Piccolo |e verfasserin |4 aut | |
| 700 | 0 | |a Sara Montecchini |e verfasserin |4 aut | |
| 700 | 0 | |a Clara Maccari |e verfasserin |4 aut | |
| 700 | 0 | |a Monica Martinelli |e verfasserin |4 aut | |
| 700 | 0 | |a Alan Di Maio |e verfasserin |4 aut | |
| 700 | 0 | |a Francesca Ferraglia |e verfasserin |4 aut | |
| 700 | 0 | |a Federica Pinardi |e verfasserin |4 aut | |
| 700 | 0 | |a Paolo Montagna |e verfasserin |4 aut | |
| 700 | 0 | |a Maria Cristina Arcangeletti |e verfasserin |4 aut | |
| 700 | 0 | |a Carlo Chezzi |e verfasserin |4 aut | |
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