Intracochlear Platelet-rich Fibrin Application in Cochlear Implantation : Intracochlear Platelet-rich Fibrin Application in Cochlear Implantation
The most common problem with cochlear implants is that their effectiveness decreases over time and they are not functional enough mainly due to fibrosis.Our aim in this study is to benefit from the anti-inflammatory effects of autologous platelet-rich fibrin to reducing the fibrotic cascade.Cochlear implant application will be performed under general anesthesia. After the postauricular incision and mastoidectomy, posterior tympanotomy will find the middle ear and from there the round window, and platelet fibrin prepared with the i-prf technique will be locally applied to the round window during the operation, and then implantation will be performed.The points where the electrode enters the cochlea will be covered with fascia.Intraoperative NRT and impedances will be measured on all electrodes in all patients, and NRT and impedance measurements will be repeated in the 1st week, 1st month, 3rd and 6th months postoperatively.Custom Sound EP 5.0 (5.0.4.136) program provided by Cochlear company will be used for these measurements..
| Medienart: |
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Klinische Studie| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
ClinicalTrials.gov - (2023) vom: 15. Sept. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
610 |
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| Anmerkungen: |
Source: Link to the current ClinicalTrials.gov record., First posted: January 31, 2022, Last downloaded: ClinicalTrials.gov processed this data on September 20, 2023, Last updated: September 20, 2023 |
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| Study ID: |
NCT05215197 |
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| Veröffentlichungen zur Studie: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
CTG00815676X |
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| 520 | |a The most common problem with cochlear implants is that their effectiveness decreases over time and they are not functional enough mainly due to fibrosis.Our aim in this study is to benefit from the anti-inflammatory effects of autologous platelet-rich fibrin to reducing the fibrotic cascade.Cochlear implant application will be performed under general anesthesia. After the postauricular incision and mastoidectomy, posterior tympanotomy will find the middle ear and from there the round window, and platelet fibrin prepared with the i-prf technique will be locally applied to the round window during the operation, and then implantation will be performed.The points where the electrode enters the cochlea will be covered with fascia.Intraoperative NRT and impedances will be measured on all electrodes in all patients, and NRT and impedance measurements will be repeated in the 1st week, 1st month, 3rd and 6th months postoperatively.Custom Sound EP 5.0 (5.0.4.136) program provided by Cochlear company will be used for these measurements. | ||
| 650 | 2 | |a Hearing Loss | |
| 650 | 2 | |a Hearing Loss, Sensorineural | |
| 650 | 4 | |a Study Type: Interventional | |
| 650 | 4 | |a Recruitment Status: Recruiting | |
| 650 | 4 | |a 610 | |
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