Targeting Glutamine Metabolism to Prevent Diabetic Cardiovascular Complications : Targeting Glutamine Metabolism to Prevent Diabetic Cardiovascular Complications
The aim of the study is to investigate the role of glutamine metabolism in the pro-inflammatory activation of macrophages in diabetes and related cardiovascular complications.The study focuses on 3 adult patients' population with different diabetic status and level of cardiovascular risk:Patients with uncomplicated type 1 or type 2 diabetes and low cardiovascular riskPatients with uncomplicated type 1 or type 2 diabetes and high cardiovascular riskPatients with complicated type 1 or type 2 diabetesParticipants (n=975) will be recruited at clinical sites, in the diabetes and cardiology departments (APHP, Bichat - Claude-Bernard Hospital and APHP, Lariboisière Hospital), over a 2-year period.The study will consist in a single visit. During a scheduled hospitalization or consultation as part of the follow-up of their diabetes or as part of the follow-up of their cardiological problems, clinical data will be collected as well as additional blood and urine samples for analyses and biobanking. There will be no other intervention specific to the study..
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Klinische Studie| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
ClinicalTrials.gov - (2023) vom: 29. Nov. Zur Gesamtaufnahme - year:2023 |
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| Sprache: |
Englisch |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
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| Anmerkungen: |
Source: Link to the current ClinicalTrials.gov record., First posted: April 21, 2020, Last downloaded: ClinicalTrials.gov processed this data on December 06, 2023, Last updated: December 06, 2023 |
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| Study ID: |
NCT04353869 |
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| Veröffentlichungen zur Studie: |
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| PPN (Katalog-ID): |
CTG003365336 |
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| 520 | |a The aim of the study is to investigate the role of glutamine metabolism in the pro-inflammatory activation of macrophages in diabetes and related cardiovascular complications.The study focuses on 3 adult patients' population with different diabetic status and level of cardiovascular risk:Patients with uncomplicated type 1 or type 2 diabetes and low cardiovascular riskPatients with uncomplicated type 1 or type 2 diabetes and high cardiovascular riskPatients with complicated type 1 or type 2 diabetesParticipants (n=975) will be recruited at clinical sites, in the diabetes and cardiology departments (APHP, Bichat - Claude-Bernard Hospital and APHP, Lariboisière Hospital), over a 2-year period.The study will consist in a single visit. During a scheduled hospitalization or consultation as part of the follow-up of their diabetes or as part of the follow-up of their cardiological problems, clinical data will be collected as well as additional blood and urine samples for analyses and biobanking. There will be no other intervention specific to the study. | ||
| 650 | 4 | |a Study Type: Observational | |
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