Collection of Blood From Patients With Prostate Cancer : Collection of Blood From Patients With Prostate Cancer
Objectives:-To obtain blood samples from patients with prostate cancer for genotyping analyses.Eligibility:- All patients seen in the NCI prostate cancer clinic are eligible.Design:Patients with a prior diagnosis of prostate cancer will be evaluated in the GMB Clinic, NCI.Blood samples will be collected after the participant signs the protocol consent form. In general, blood will be collected for genomic DNA one time for this study. Extra samples may be requested if the original sample was not enough. The additional sample can range from one to two tubes of blood (approximately 2-3 teaspoons total). Genomic DNA and white blood cells will each be extracted from these samples to be utilized for genotyping and establishment of individual cell lines.Genetic variance will be correlated with prostate cancer prognosis (i.e. time from diagnosis to death) and prognostic indicators (i.e. histological tumor grade).Blood samples for the extraction of cell-free DNA (cfDNA) and cell-free RNA (cfRNA) may be collected at multiple timepoints for future investigationsHealthy controls will not be compared and no correlations will be made with prostate cancer susceptibility..
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Klinische Studie| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
ClinicalTrials.gov - (2024) vom: 19. Apr. Zur Gesamtaufnahme - year:2024 |
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| Sprache: |
Englisch |
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| Links: |
Volltext [kostenfrei] |
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| Themen: |
610 |
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| Anmerkungen: |
Source: Link to the current ClinicalTrials.gov record., First posted: June 18, 2009, Last downloaded: ClinicalTrials.gov processed this data on April 24, 2024, Last updated: April 24, 2024 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
CTG000739324 |
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| 520 | |a Objectives:-To obtain blood samples from patients with prostate cancer for genotyping analyses.Eligibility:- All patients seen in the NCI prostate cancer clinic are eligible.Design:Patients with a prior diagnosis of prostate cancer will be evaluated in the GMB Clinic, NCI.Blood samples will be collected after the participant signs the protocol consent form. In general, blood will be collected for genomic DNA one time for this study. Extra samples may be requested if the original sample was not enough. The additional sample can range from one to two tubes of blood (approximately 2-3 teaspoons total). Genomic DNA and white blood cells will each be extracted from these samples to be utilized for genotyping and establishment of individual cell lines.Genetic variance will be correlated with prostate cancer prognosis (i.e. time from diagnosis to death) and prognostic indicators (i.e. histological tumor grade).Blood samples for the extraction of cell-free DNA (cfDNA) and cell-free RNA (cfRNA) may be collected at multiple timepoints for future investigationsHealthy controls will not be compared and no correlations will be made with prostate cancer susceptibility. | ||
| 650 | 2 | |a Prostatic Neoplasms | |
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