电子支气管镜肺泡灌洗术在重症监护室机械通气伴有肺不张病人中的应用 : = The application of electronic bronchoscope alveolar lavage in patients with mechanical ventilation and atelectasis in intensive care unit

目的探讨电子支气管镜肺泡灌洗术在重症监护室(ICU)机械通气伴有肺不张病人中的应用效果。方法收集2016年6月至2018年6月安徽省立医院ICU 100例机械通气同时伴有肺不张病人的临床样本,按照随机数字表法分成观察组和对照组各50例。对照组常规抗生素治疗,定时翻身、拍背、吸痰等常规护理。观察组在对照组基础上,定期给予电子支气管镜肺泡灌洗治疗。对比两组病人治疗1周后动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)、动脉血氧饱和度(SaO2)等多项动脉血气指标的变化,肺复张情况及临床治疗效果。结果 1周前观察组和对照组病人的PaO2分别为(72.5±14.1)mmHg和(70.3±15.0)mmHg,SaO2分别为(88.6±4.8)%和(88.8±3.6)%,治疗1周后,观察组与对照组病人的PaO2分别为(81.7±11.7)mmHg和(76.1±13.1)mmHg,SaO2分别为(95.6±4.0)%和(91.4±2.6)%,观察组与对照组病人的PaO2、SaO2均较前改善,但观察组改善更为显著,均差异有统计学意义(P<0.05)。观察组肺复张总有效率88%,显著高于对照组的64%,差异有统计学意义(P<0.01)。与对照组相比,观察组病人使用抗生素时间减少,机械通气时间及住ICU天数缩短,均差异有统计学意义(P<0.01)。结论 ICU机械通气伴有肺不张病人定期给予电子支气管镜肺泡灌洗治疗,可提高临床疗效,促进病人康复。.

Objective To investigate the effect of electronic bronchoscope alveolar lavage in ICU patients with mechanical ventilation and atelectasis.Methods Clinical samples of 100 patients with mechanical ventilation and atelectasis in ICU of Anhui Provincial Hospital from June 2016 to June 2018 were collected and divided into observation group and control group according to the random number table method,50 patients each group.The control group received routine antibiotic treatment,routine nursing such as turning over,backslapping and sputum aspiration.On the basis of the control group,the observation group was regularly treated with electronic bronchoscope alveolar lavage.The changes of arterial blood gas indexes,such as arterial partial oxygen pressure(PaO2),arterial partial carbon dioxide pressure(PaCO2)and arterial oxygen saturation(SaO2),as well as pulmonary reexpansion and clinical treatment effect were compared between the two groups after 1 week of treatment.Results The PaO2 in the observation group and the control group 1 week ago were(72.5 ± 14.1)mmHg and(70.3 ± 15.0)mmHg,respectively,and the SaO2 were(88.6 ± 4.8)% and(88.8 ± 3.6)%,respectively.After 1 week of treatment,the PaO2 in the observation group and the control group were(81.7±11.7)mmHg and(76.1±13.1)mmHg,respectively,and the SaO2 were(95.6±4.0)% and(91.4±2.6)%,respectively.The PaO2 and SaO2 of the patients in the observation group and the control group were improved compared with the former,but the improvement was more significant in the observation group,and the differences were statistically significant(P<0.05).The total effective rate of pulmonary reexpansion in the observation group was 88%,which was significantly higher than 64% in the control group,and the difference was statistically significant(P<0.01).Compared with the control group,the duration of antibiotic use,mechanical ventilation time and length of ICU stay in the observation group were reduced,with statistically significant differences(P<0.01).Conclusion Patients with mechanical ventilation accompanied by atelectasis in ICU are regularly treated with electronic bronchoscope alveolar lavage,which can improve the clinical efficacy and promote the recovery of patients..

Medienart:

E-Artikel

Erscheinungsjahr:

2019-12-05 16:14

2019

Erschienen:

2019-12-05 16:14

Enthalten in:

Zur Gesamtaufnahme - year:2019

Enthalten in:

An hui yi yao - (2019), 12 vom: 05 16:14. Dez., Seite 2386-2389

Original Letters: Enthalten in 安徽医药 (DE-600)2991693-8 (DE-600)2991693-8 安徽省合肥市

Reihe:

China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health

Sprache:

Chinesisch

Weiterer Titel:

The application of electronic bronchoscope alveolar lavage in patients with mechanical ventilation and atelectasis in intensive care unit

Beteiligte Personen:

刘路 [VerfasserIn]
梅清 [Sonstige Person]
潘爱军 [Sonstige Person]

Links:

oversea.cnki.net [lizenzpflichtig]

Themen:

中国科学技术大学附属第一医院(安徽省立医院)重症医学科
临床医学
内科学
医药、卫生
医药卫生科技
呼吸,人工
呼吸系及胸部疾病
支气管肺泡灌洗
支气管镜检查
治疗学
肺不张
血气分析
重症监护病房
Blood gas analysis
Bronchoalveolar lavage
Bronchoscopy
Clinical Medicine
Disease of Respiratory System
Emergency Medicine
Intensive care unit
Medicine & Public Health
Pulmonary atelectasis
Respiration,artificial

Anmerkungen:

Author info:LIU Lu;MEI Qing;PAN Aijun;Department of Critical Care Medicine,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

CAJ647477432