高脂低糖膳食对慢性阻塞性肺疾病机械通气患者呼吸功能状况影响的meta分析 : = Meta-analysis of the effect of high-fat and low-sugar diet on respiratory function in patients with mechanical ventilation of COPD
目的系统评价高脂低糖膳食对慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)机械通气患者呼吸功能状况的影响。方法计算机检索中国知网(CNKI)、维普数据库(VIP)、万方数据库、PubMed、EMbase等中英文数据库。搜集2019年10月前发表的有关高脂低糖膳食和COPD机械通气的中英文随机对照试验(RCTs),检索时间自2009年1月至2019年10月。由2位研究员分别独立的筛选符合纳入和排除标准的文献后汇总意见并提取资料,采用Cochrane偏倚风险评估工具对文献质量进行评价。结果共纳入15个RCTs,包括1 146例患者。Meta分析结果显示,COPD机械通气患者每分钟通气量(VE)[MD=-1.4,Z=8.23,P<0.01, 95%CI-1.74,-1.07),每分钟二氧化碳产生量(VCO_2)(MD=-42.61,Z=8.65,P<0.01, 95%CI-52.26,-32.96),每分钟耗氧量(VO_2)(MD=-30.16,Z=7.37,P<0.01, 95%CI-38.18,-22.14),呼吸商(RQ)(MD=-0.08,Z=19.3,P<0.01, 95%CI-0.08,-0.07),动脉血二氧化碳分压(PaCO_2)(MD=-1.13,Z=5.93,P<0.01, 95%CI-1.5,-0.76),动脉氧分压(PaO_2)(MD=1.24,Z=8.02,P<0.01, 95%CI 0.94, 1.54),应用高脂低糖组均优于对照组。结论高脂低糖膳食有助于改善COPD机械通气患者的通气状况,减少CO_2的产生,降低PaCO_2,提高PaO_2,纠正呼吸衰竭。.
Objective To systematically evaluate the effects of high-fat and low-sugar diet on respiratory function in patients with mechanical ventilation of chronic obstructive pulmonary disease(COPD). Methods Chinese and English databases, such as China national knowledge infrastructure(CNKI), VIP database(VIP), Wanfang database, PubMed, EMbase were searched. Randomized controlled trials(RCTs) in Chinese and English on high-fat and low-sugar diet and COPD mechanical ventilation published in 2019 were collected from January to October. Two researchers independently screened the literature that met the inclusion and exclusion criteria, summarized the opinions and extracted the data. The Cochrane bias risk assessment tool was used to evaluate the quality of the literature. Results A total of 15 RCTs were collected, including 1 146 patients. Meta-analysis showed the data of high-fat and low-sugar group were higher than those of control group in many aspects, such as VE(MD=-1.4, Z=8.23, P<0.01, 95%CI-1.74,-1.07), VCO_2(MD=-42.61, Z=8.65, P<0.01, 95%CI-52.26,-32.96), VO_2(MD=-30.16, Z=7.37, P<0.01, 95%CI-38.18,-22.14), RQ(MD=-0.08, Z=19.3, P<0.01, 95%CI-0.08,-0.07), PaCO_2(MD=-1.13, Z=5.93, P<0.01, 95%CI-1.5,-0.76), PaO_2(MD=1.24, Z=8.02, P<0.01, 95%CI 0.94, 1.54). Conclusion High-fat and low-sugar diets can improve respiratory function in patients with COPD mechanical ventilation, reduce the production of CO, lower PaCO_2, raise PaO_2, and correct respiratory failure..
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019-12-20 2019 |
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| Erschienen: |
2019-12-20 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2019 |
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| Enthalten in: |
Lin chuang hui cui - (2019), 12 vom: 20. Dez., Seite 1108-1114 Original Letters: Enthalten in 临床荟萃 (DE-600)2990451-1 (DE-600)2990451-1 河北省石家庄市 |
| Reihe: |
China Academic Journals (CAJ), E, 医药卫生科技 = Medicine & Public Health |
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| Sprache: |
Chinesisch |
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| Weiterer Titel: |
Meta-analysis of the effect of high-fat and low-sugar diet on respiratory function in patients with mechanical ventilation of COPD |
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| Beteiligte Personen: |
周衍香 [VerfasserIn] |
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| Links: |
oversea.cnki.net [lizenzpflichtig] |
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| Anmerkungen: |
Author info:Zhou Yanxiang;Mei Bo;Liu Zhongyang;Postgraduate Training Base of the People's Liberation Army Joint Service Support Force No.967 Hospital, Jinzhou Medical University;Department of Respiratory Medicine,the People's Liberation Army Joint Service Support Force No.967 Hospital |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
CAJ647365286 |
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| 245 | 1 | 0 | |a 高脂低糖膳食对慢性阻塞性肺疾病机械通气患者呼吸功能状况影响的meta分析 |b = Meta-analysis of the effect of high-fat and low-sugar diet on respiratory function in patients with mechanical ventilation of COPD |
| 246 | 3 | 1 | |a Meta-analysis of the effect of high-fat and low-sugar diet on respiratory function in patients with mechanical ventilation of COPD |
| 264 | 1 | |c 2019-12-20 | |
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| 500 | |a Author info:Zhou Yanxiang;Mei Bo;Liu Zhongyang;Postgraduate Training Base of the People's Liberation Army Joint Service Support Force No.967 Hospital, Jinzhou Medical University;Department of Respiratory Medicine,the People's Liberation Army Joint Service Support Force No.967 Hospital | ||
| 520 | |a 目的系统评价高脂低糖膳食对慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)机械通气患者呼吸功能状况的影响。方法计算机检索中国知网(CNKI)、维普数据库(VIP)、万方数据库、PubMed、EMbase等中英文数据库。搜集2019年10月前发表的有关高脂低糖膳食和COPD机械通气的中英文随机对照试验(RCTs),检索时间自2009年1月至2019年10月。由2位研究员分别独立的筛选符合纳入和排除标准的文献后汇总意见并提取资料,采用Cochrane偏倚风险评估工具对文献质量进行评价。结果共纳入15个RCTs,包括1 146例患者。Meta分析结果显示,COPD机械通气患者每分钟通气量(VE)[MD=-1.4,Z=8.23,P<0.01, 95%CI-1.74,-1.07),每分钟二氧化碳产生量(VCO_2)(MD=-42.61,Z=8.65,P<0.01, 95%CI-52.26,-32.96),每分钟耗氧量(VO_2)(MD=-30.16,Z=7.37,P<0.01, 95%CI-38.18,-22.14),呼吸商(RQ)(MD=-0.08,Z=19.3,P<0.01, 95%CI-0.08,-0.07),动脉血二氧化碳分压(PaCO_2)(MD=-1.13,Z=5.93,P<0.01, 95%CI-1.5,-0.76),动脉氧分压(PaO_2)(MD=1.24,Z=8.02,P<0.01, 95%CI 0.94, 1.54),应用高脂低糖组均优于对照组。结论高脂低糖膳食有助于改善COPD机械通气患者的通气状况,减少CO_2的产生,降低PaCO_2,提高PaO_2,纠正呼吸衰竭。 | ||
| 520 | |a Objective To systematically evaluate the effects of high-fat and low-sugar diet on respiratory function in patients with mechanical ventilation of chronic obstructive pulmonary disease(COPD). Methods Chinese and English databases, such as China national knowledge infrastructure(CNKI), VIP database(VIP), Wanfang database, PubMed, EMbase were searched. Randomized controlled trials(RCTs) in Chinese and English on high-fat and low-sugar diet and COPD mechanical ventilation published in 2019 were collected from January to October. Two researchers independently screened the literature that met the inclusion and exclusion criteria, summarized the opinions and extracted the data. The Cochrane bias risk assessment tool was used to evaluate the quality of the literature. Results A total of 15 RCTs were collected, including 1 146 patients. Meta-analysis showed the data of high-fat and low-sugar group were higher than those of control group in many aspects, such as VE(MD=-1.4, Z=8.23, P<0.01, 95%CI-1.74,-1.07), VCO_2(MD=-42.61, Z=8.65, P<0.01, 95%CI-52.26,-32.96), VO_2(MD=-30.16, Z=7.37, P<0.01, 95%CI-38.18,-22.14), RQ(MD=-0.08, Z=19.3, P<0.01, 95%CI-0.08,-0.07), PaCO_2(MD=-1.13, Z=5.93, P<0.01, 95%CI-1.5,-0.76), PaO_2(MD=1.24, Z=8.02, P<0.01, 95%CI 0.94, 1.54). Conclusion High-fat and low-sugar diets can improve respiratory function in patients with COPD mechanical ventilation, reduce the production of CO, lower PaCO_2, raise PaO_2, and correct respiratory failure. | ||
| 610 | 2 | 4 | |a 锦州医科大学解放军联勤保障部队第九六七医院研究生培养基地 |
| 610 | 2 | 4 | |a 解放军联勤保障部队第九六七医院呼吸内科 |
| 650 | 4 | |a 呼吸系及胸部疾病 | |
| 650 | 4 | |a 内科学 | |
| 650 | 4 | |a 医药、卫生 | |
| 650 | 4 | |a Disease of Respiratory System | |
| 650 | 4 | |a 医药卫生科技 | |
| 650 | 4 | |a Medicine & Public Health | |
| 650 | 4 | |a 肺疾病,慢性阻塞性 | |
| 650 | 4 | |a 膳食,高脂 | |
| 650 | 4 | |a 膳食,低碳水化合物 | |
| 650 | 4 | |a 呼吸,人工 | |
| 650 | 4 | |a 呼吸功能试验 | |
| 650 | 4 | |a pulmonary disease, chronic obstructive | |
| 650 | 4 | |a diet, high-fat | |
| 650 | 4 | |a diet, carbohydrate-restricted | |
| 650 | 4 | |a respiration, artificial | |
| 650 | 4 | |a respiratory function tests | |
| 700 | 0 | |a 梅波 |4 oth | |
| 700 | 0 | |a 刘中洋 |4 oth | |
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